ID A0A484DBL3_PERFV Unreviewed; 623 AA.
AC A0A484DBL3;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 28-JUN-2023, entry version 11.
DE RecName: Full=FERM domain-containing protein {ECO:0000259|PROSITE:PS50057};
GN ORFNames=EPR50_G00051390 {ECO:0000313|EMBL:TDH12896.1};
OS Perca flavescens (American yellow perch) (Morone flavescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Percoidei; Percidae; Percinae; Perca.
OX NCBI_TaxID=8167 {ECO:0000313|EMBL:TDH12896.1, ECO:0000313|Proteomes:UP000295070};
RN [1] {ECO:0000313|EMBL:TDH12896.1, ECO:0000313|Proteomes:UP000295070}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YP-PL-M2 {ECO:0000313|EMBL:TDH12896.1};
RC TISSUE=Blood {ECO:0000313|EMBL:TDH12896.1};
RA Feron R., Morvezen R., Bestin A., Haffray P., Klopp C., Zahm M., Cabau C.,
RA Roques C., Donnadieu C., Bouchez O., Christie M., Larson W., Guiguen Y.;
RT "A chromosome-scale genome assembly of the yellow perch, Perca
RT flavescens.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDH12896.1}.
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DR EMBL; SCKG01000005; TDH12896.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A484DBL3; -.
DR STRING; 8167.A0A484DBL3; -.
DR OrthoDB; 2912597at2759; -.
DR Proteomes; UP000295070; Chromosome 5.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd17102; FERM_F1_FRMD3; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF8; FERM DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000295070};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 554..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..298
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 377..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 71012 MW; B7E2B9ADA087E38F CRC64;
MKMLRFRSPS IRSLDQEVLC TIRLLDDSEV SCSIQRDTKG QFLLDHVCNH YNLLEKDYFG
IRYVDPEKQR HWLEPNKPVV RQMKSQQPYT MCFRVKFYPH EPIKIKEELT RYLLYLQLKR
DIYHGRLLCP FAEAAYLGAC IIQAELGDYD PEEHPSDYIR DFKLFPKQSL KLERKIMEIH
KNELRGQCAA FAELNMLQKA HSLETYGVDP HPCKDFTGST AFLGFTATGF VVFQGNKRIH
LLKWADVSKL KFEGKTFYVI GIQKEKKLVL TFHTSTPAAC KHLWKCGVEN QAFYKCAKSS
QIKTVSSSNI FFKGSRFRYS GRVAKEVIEA SSKIQREPPE VCRAQFGQSR SFNSLSHKNL
IMNMEPLVPA LPSTNEYEET ATDNGVVSVK DSVPLSPLKT SAAPPDTEQR SDEGGNSALG
NNMQPSRVSM ETSNLRPQTP KAKDEVEEDD EASSPLTISE LVYSPCASML STPVDDSQGG
VDLLFSSPVQ SPARLLRELH ADPDIQAQLE AERERDRAYE RTRLAARSRM GGVLTSSLLR
LSSNERVNAC LLSVARFVAV VMGVLLVTVP TLLLLLESDI DVSFLHEIRQ TPEFEQFHYE
YYCPLRRWIL CRISMAMENL WSD
//
