ID A0A484FIM7_COLOR Unreviewed; 1823 AA.
AC A0A484FIM7;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Guanine nucleotide exchange factor LTE1 {ECO:0000313|EMBL:TDZ17531.1};
GN Name=LTE1 {ECO:0000313|EMBL:TDZ17531.1};
GN ORFNames=Cob_v009689 {ECO:0000313|EMBL:TDZ17531.1};
OS Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS
OS 414 / MAFF 240422) (Cucumber anthracnose fungus) (Colletotrichum
OS lagenarium).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum orbiculare species complex.
OX NCBI_TaxID=1213857 {ECO:0000313|EMBL:TDZ17531.1, ECO:0000313|Proteomes:UP000014480};
RN [1] {ECO:0000313|Proteomes:UP000014480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422
RC {ECO:0000313|Proteomes:UP000014480};
RX PubMed=23252678; DOI=10.1111/nph.12085;
RA Gan P., Ikeda K., Irieda H., Narusaka M., O'Connell R.J., Narusaka Y.,
RA Takano Y., Kubo Y., Shirasu K.;
RT "Comparative genomic and transcriptomic analyses reveal the hemibiotrophic
RT stage shift of Colletotrichum fungi.";
RL New Phytol. 197:1236-1249(2013).
RN [2] {ECO:0000313|Proteomes:UP000014480}
RP GENOME REANNOTATION.
RC STRAIN=104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422
RC {ECO:0000313|Proteomes:UP000014480};
RX PubMed=30893003; DOI=10.1094/MPMI-12-18-0352-A;
RA Gan P., Tsushima A., Narusaka M., Narusaka Y., Takano Y., Kubo Y.,
RA Shirasu K.;
RT "Genome sequence resources for four phytopathogenic fungi from the
RT Colletotrichum orbiculare species complex.";
RL Mol. Plant Microbe Interact. 32:1088-1090(2019).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDZ17531.1}.
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DR EMBL; AMCV02000028; TDZ17531.1; -; Genomic_DNA.
DR STRING; 1213857.A0A484FIM7; -.
DR Proteomes; UP000014480; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF364; GUANINE NUCLEOTIDE EXCHANGE FACTOR LTE1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000014480}.
FT DOMAIN 406..530
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 1576..1820
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 36..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 92..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 696..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 803..823
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 972..992
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1126..1154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1269..1293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1315..1340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1352..1394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1407..1493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1518..1548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..244
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..634
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1321..1340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1362..1377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1450..1474
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1530..1544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1823 AA; 200335 MW; 56792580B8E2CFCF CRC64;
MASKLTPASI TRCPHLSTRL CPSFASFSSF ATLSSHRSAS TQPIKPESSS SPRPEVCKTV
KNFDWRKRRL RYRQYREMDQ QDAHARALEA VGSRDGEKVG GMESTTQPPN GGSAGREGRQ
FTVANVGNNG RIYLRPTVRP ANQRYPQPNF VFPITPPGTA GLDALTEQQR QQDATDLHLS
QWTNTPPTPA TPATPATAAS PPTVSSSKRY FSAHASRPSQ HRRAHSDSTA HDGNTSRHSE
AEGFKIVISK PGDEKRSKTM EDLDTPHIPL IDIDIPNWKL GHPRFTARGT PFFRGSSYAP
TDEFPRSSNL SFPHRSQTGE LTSRIPDSTA SRRPSPISIP QIRLPPMDHP VGAAASLSPP
PMTTPRLPLT RSTYLSTHLV IEPAMFDALT FKPTCDDRSI VRYSPSTGAV TAATPPRLVA
EITSPSFCDY ELISDFFLTY RAFLEPADLL RMLMARLRWA AGRNDETGMV VRVRTFVAMR
HWILNYFMDD FVIEYGLRVT FCNLLNDMVT EISTEPRGRK VQLKILAELK KCWRQVCAHF
WDGPEFDPLS GPNVPIHPGG IAGHRNPSLD PSFWEREDAV PQLESLFAPI MEDQEQISFR
AEVSRAGHIG ESIELAERPC TPENHHDHEA DRRQAASPTS IASVDIVSCS FPGKTTRMGQ
QTGNHPLAAH PVAPGSSIYS NAGPVATTPK ALVGKRVRPG QGHKRSGSLT DSLRERDYAA
DKSNIQDTDL LMSLPFAGSL VRGNVMPPGQ PFVEVMSPSL HGEFQRHTTV FQLPPEQRSA
ASAMSGQGMR KLIGSVRRAL STKDQGVSPT QGNFINISPI GPRGATTNRL PGTAIVPQAR
PRLNGIRPPV RVDLLGAEIV EDFKKAVRED AAADAAAEAE RRGYRGYLNP GLGVMHSAVP
EDALEYSTAH LVSSYGSIQG HDITRPLSDM AITTGSKSIV IVDDTVSFPL PAMHGALPAA
DSVDEFGDNF VPTGADPTPP NTPPGDSMGT PRRSSYLLNQ HVMRPSLSAD PLPPFVPDLA
TLGNDRSSCL SAQPDRPISD IEGSSNRPAL SRFTKEHIRQ KSSRTNRSFS SAAIPRRIAS
FGSAFNPRST VKSFDATTYS EGSVSDERES SPIPQPLRIL RRRPGGDLRA FNRGGDMDGL
PLRTSRSTGS LTTYSDSLRS SYLPSPNHDT SAFVDVVSSE FSHQGNADTF SLGAMAEPST
KRQISLFSTH SSKPIMRPSF EAEAQKLAQI PDDIDDDGGV ESALLKLEGK YEKKMFKLSM
EPTNAPIQLP PGLDVAGPVA ADSESPKSER KERRHLQVLP GDAILAHQHL HGVESHAGSL
EAPQRPQTAT DSVASNNSAG SYCSIPLLER DLTDDGKSKT NTREWTNMSI LQGHDEDSTP
GETSRPMFER SLSYTSSYEL VRKTESLEKI KSGDSVPAPS EQSFLDDDSD LEDLGSDLSS
ELSAEVLDSD DFAPEPKPTK THRGPSEEHA DYPLREASAS PSDSQDPPSP PMTLVQALRM
SPEAATVPEL HEHQVYQQKP LPPTPDITPI AANPSESSPD PTGTKAALRG QPKFLESERE
SSLTFSVHLP FILAFESEIL AQQFTLIEKD ALNEIDWKEL IDMGWKHATN NDSRSWVDFL
RNTDAHGVEV VIARFNIMVK WACSEIVLTQ NIEERARCII KFIHIAAHCR RYRNFASMSQ
ITMALTSMEI SRLASTWTMV PPHDIKTLED LEGLISPMRN FYNLRAEMES GSNTGCIPFV
GIYTHDLLFN AQRPSEIASS PTTAPLINFE RCRYSATIVK TLLRLLEDSS HYDFQPVEGI
TERCLWMSAL TDEEIRKHSH LLE
//
