ID A0A484ICG2_9ARCH Unreviewed; 270 AA.
AC A0A484ICG2;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Translation initiation factor IF-2 subunit alpha {ECO:0000313|EMBL:VFJ15015.1};
GN ORFNames=NFRAN_2693 {ECO:0000313|EMBL:VFJ15015.1};
OS Candidatus Nitrosocosmicus franklandus.
OC Archaea; Nitrososphaerota; Nitrososphaeria; Nitrososphaerales;
OC Nitrososphaeraceae; Nitrosocosmicus.
OX NCBI_TaxID=1798806 {ECO:0000313|EMBL:VFJ15015.1, ECO:0000313|Proteomes:UP000294299};
RN [1] {ECO:0000313|EMBL:VFJ15015.1, ECO:0000313|Proteomes:UP000294299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NFRAN1 {ECO:0000313|EMBL:VFJ15015.1};
RA Lehtovirta-Morley E L.;
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the eIF-2-alpha family.
CC {ECO:0000256|ARBA:ARBA00007223}.
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DR EMBL; LR216287; VFJ15015.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A484ICG2; -.
DR KEGG; nfn:NFRAN_2693; -.
DR OrthoDB; 84794at2157; -.
DR Proteomes; UP000294299; Chromosome nfran.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04452; S1_IF2_alpha; 1.
DR Gene3D; 3.30.70.1130; EIF_2_alpha; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR003029; S1_domain.
DR InterPro; IPR044126; S1_IF2_alpha.
DR InterPro; IPR024055; TIF2_asu_C.
DR InterPro; IPR024054; TIF2_asu_middle_sf.
DR InterPro; IPR011488; TIF_2_asu.
DR PANTHER; PTHR10602; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1; 1.
DR PANTHER; PTHR10602:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1; 1.
DR Pfam; PF07541; EIF_2_alpha; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF110993; eIF-2-alpha, C-terminal domain; 1.
DR SUPFAM; SSF116742; eIF2alpha middle domain-like; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:VFJ15015.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000294299}.
FT DOMAIN 14..85
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
SQ SEQUENCE 270 AA; 30413 MW; 1C19E16BE5666CDC CRC64;
MVSISDTKKL PELGEIVIVT VKEVTGHGAY VTLDEYDNLT AFLHISEIAT GWIRNIERYV
KPKQKTVLKV IRVNPTRSEV DLSLKQVTGE EKKSKIIEVK KDEKGANFMD IIKTKLGYDL
NQIKEIEEKI AQKYDFIYDA FEAVAIKGPD VLASLDLKPE VIEAIEAESK KIQIPHIEVR
ALLEITVRKG NGIDIIKNVL SSVEGSKNNS KVDITYVGAP RYRITVTAEN FKIAEKALNQ
AIEKIKTSIE KNSGTFKFLR EESKKTHTNI
//
