ID   A0A485LKF7_9STRA        Unreviewed;       776 AA.
AC   A0A485LKF7;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Aste57867_20756 protein {ECO:0000313|EMBL:VFT97435.1};
GN   Name=Aste57867_20756 {ECO:0000313|EMBL:VFT97435.1};
GN   ORFNames=As57867_020688 {ECO:0000313|EMBL:KAF0687517.1},
GN   ASTE57867_20756 {ECO:0000313|EMBL:VFT97435.1};
OS   Aphanomyces stellatus.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Aphanomyces.
OX   NCBI_TaxID=120398 {ECO:0000313|EMBL:VFT97435.1, ECO:0000313|Proteomes:UP000332933};
RN   [1] {ECO:0000313|EMBL:VFT97435.1, ECO:0000313|Proteomes:UP000332933}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 568.67 {ECO:0000313|EMBL:VFT97435.1};
RA   Gaulin E., Dumas B.;
RL   Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KAF0687517.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CBS 578.67 {ECO:0000313|EMBL:KAF0687517.1};
RA   Gaulin E.;
RT   "Genomics analysis of Aphanomyces spp. identifies a new class of oomycete
RT   effector associated with host adaptation.";
RL   Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC         Evidence={ECO:0000256|ARBA:ARBA00001973};
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DR   EMBL; VJMH01006905; KAF0687517.1; -; Genomic_DNA.
DR   EMBL; CAADRA010006931; VFT97435.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A485LKF7; -.
DR   Proteomes; UP000332933; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd01100; APPLE_Factor_XI_like; 3.
DR   Gene3D; 3.30.30.180; -; 1.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   Gene3D; 3.50.4.10; Hepatocyte Growth Factor; 2.
DR   InterPro; IPR000177; Apple.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR003609; Pan_app.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF14295; PAN_4; 3.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SMART; SM00223; APPLE; 3.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   SUPFAM; SSF57414; Hairpin loop containing domain-like; 1.
DR   PROSITE; PS50948; PAN; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000332933};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..776
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5033826604"
FT   DOMAIN          101..173
FT                   /note="Apple"
FT                   /evidence="ECO:0000259|PROSITE:PS50948"
FT   REGION          172..234
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   776 AA;  83917 MW;  D77C3794DCD548A4 CRC64;
     MRLLRPFAVV VSFLGHLTLT NASASTHCSA VVQDTDYYGN DIKATQPSSI DGCCTDCQAT
     PGCHLFVWRY GNCYLKYMQG AASVALGAQA SMLPTAVPST CGPIEPNTDY YGNDIRAASR
     ASVDDCCAEC QATSGCKLFV WRYGNCYLKY AKGASSVANG ALAVSAMAFP RTTSPTTTTP
     TTTTSLHTTT TTPPTRTPAP ITTTASPTSR PTTTATTTTT TAVPMTTTPS PTTPSVCSRL
     VQNVNYDGFD LSQVPNVATA GACCTLCQAT PKCFLFVWLD GVCRLKSARG MSSLQAGAVS
     ATVLHPLCPP RVRQSWDAMT TDDQTLFVQA IALAMDKGFF ADFVYIHADH MSNYEAHNTC
     VFLFWHRKFL LGFETMLRSL GPEFACLTLP YMDYVQQYAA FQRGKCTSIA TCAAATQALG
     GNAPGSSSST LSFFGYTYPQ TTCITAPPLN HLCDPAAPSC ARCLPRADWS TISLPADLNF
     ETIRQNVFAG NNSILAASRA IELSPHNVMH STLNGPMNNL FVSPMDPIFY LHHTTIDLLH
     TIYYHCNVEP LQLPTAAARQ TDTRSFQGCV TNNNEPVGPK STVLMRHQLS NGNVLDVTDP
     ASPLAPFFAD LPTEYWALTD TRDLGTFSYS YGIRNLLGDL YTNCATSGTT HQAEAVIDEA
     TTHAIDHVVT TVKPSSSAAI LFDFRHAVYA AAAAVGLTEV EADVEIQKMQ VMLHQECLPG
     DVVDFTPEFK AMWHTDSPSS FKTLRALEAG ELTMRIPTWR ALNKQFFACP PDDEVP
//