ID A0A493SUV8_ANAPP Unreviewed; 433 AA.
AC A0A493SUV8;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Interferon regulatory factor 2 {ECO:0000313|Ensembl:ENSAPLP00000017376.1};
GN Name=IRF2 {ECO:0000313|Ensembl:ENSAPLP00000017376.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000017376.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000017376.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000017376.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A493SUV8; -.
DR STRING; 8840.ENSAPLP00000017376; -.
DR Ensembl; ENSAPLT00000023144.1; ENSAPLP00000017376.1; ENSAPLG00000015442.2.
DR GeneTree; ENSGT00940000159063; -.
DR OMA; SSWPPFA; -.
DR Proteomes; UP000016666; Chromosome 4.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005925; C:focal adhesion; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF22; INTERFERON REGULATORY FACTOR 2; 1.
DR Pfam; PF00605; IRF; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016666}.
FT DOMAIN 90..198
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
FT REGION 399..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 433 AA; 48663 MW; 247A7DDD9A9B6D00 CRC64;
MLLTCNCQKP RYVFVPLWSV LSQGTVSGSA FCLYFLPCVA AEEQGPCLGC QQHAAFTLQR
SMAPQKKPTL PSSWTSRQLL AVQVTMPVER MRMRPWLEEQ INSNTIPGLK WINKEKKIFQ
IPWMHAARHG WDVEKDAPLF RNWAIHTGKY QSGVDKPDPK TWKANFRCAM NSLPDIEEVK
DKSIKKGNNA FRVYRMLPLS ERPSKKGKKT KSEKDDKFKQ IKQEPVESSF GINGLNDVTS
DYFLPSSIKN EVDSTVNIVV VGQPHLDGSS EEQVIVANPP DVCQVVEVTT ESDEQPLSMS
QLYPLQISPV SSYAESETTD SVPSDEENAE GRLHWQKKNI EGKQYLSNLG MRNTSHTLPS
MATFVANKPD LQVTIKEESC PLPYNSSWPP FPDIPLPQVV STASTSSSRP DRETRASVIK
KTSDITQSRV KSC
//
