ID   A0A493SVD1_ANAPP        Unreviewed;       477 AA.
AC   A0A493SVD1;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=IF rod domain-containing protein {ECO:0000259|PROSITE:PS51842};
OS   Anas platyrhynchos platyrhynchos (Northern mallard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Anas.
OX   NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000017546.1, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Ensembl:ENSAPLP00000017546.1, ECO:0000313|Proteomes:UP000016666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT   "A new Pekin duck reference genome.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000017546.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|RuleBase:RU000685}.
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DR   AlphaFoldDB; A0A493SVD1; -.
DR   STRING; 8840.ENSAPLP00000017546; -.
DR   Ensembl; ENSAPLT00000018722.1; ENSAPLP00000017546.1; ENSAPLG00000019722.1.
DR   GeneTree; ENSGT00940000161685; -.
DR   OMA; VHQEDDV; -.
DR   Proteomes; UP000016666; Chromosome 23.
DR   GO; GO:0005883; C:neurofilament; IEA:InterPro.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0061564; P:axon development; IEA:InterPro.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   Gene3D; 1.20.5.170; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR033183; NF-H.
DR   PANTHER; PTHR23214:SF1; NEUROFILAMENT HEAVY POLYPEPTIDE; 1.
DR   PANTHER; PTHR23214; NEUROFILAMENT TRIPLET H PROTEIN; 1.
DR   Pfam; PF00038; Filament; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW   ECO:0000256|RuleBase:RU000685};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666}.
FT   DOMAIN          1..36
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   REGION          107..408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..140
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        141..158
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..190
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        191..206
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        208..222
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        231..259
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        300..351
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        363..399
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   477 AA;  52143 MW;  6996F8645CB705B6 CRC64;
     MARHLREYQD LLNVKMALDI EIAAYRKLLE GEETRFSAFS GSITGPIFTH RQPSVTIAST
     KIQKTKIEPP KLKVQHKFVE EIIEETKVED EKSEMEDALA AIAEEMAAKA QQEEQEEEKA
     EEAAEEEAVS EKAAAEQAAA PEEEEKEEEA EEEEAAKSDA AEEGGSEKEE IEEKEEGEEA
     EEEEEEAEAK GKAEEVEAKV EKVKTPPAKS PPKSPPKSPV TEPAKGVPKE PAAEAVKEQK
     VEKGAEKAAK EEEKAASPEK PATPKVTSPE KPATPEKPAT PEKPASPEKP ATPEKAVTPE
     KPASPEKPRS PEKTATPEKP RSPEKPATPE KPRSPEKPAS PVKDEKAAVE ETVTVTKVTK
     VSAEVEASKE SRKEDIAVNG EVEEKKEESK EEEEDKGVVT NGLDVSPVDD KGEKIVVTKK
     AEKIISEGGD STTTYITKSV TVTQKVEEHE ESFEEKLVST KKVEKVTSHA VVKEMKE
//