ID A0A493T155_ANAPP Unreviewed; 993 AA.
AC A0A493T155;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Polyhomeotic homolog 1 {ECO:0000313|Ensembl:ENSAPLP00000019664.1};
GN Name=PHC1 {ECO:0000313|Ensembl:ENSAPLP00000019664.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000019664.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000019664.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000019664.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A493T155; -.
DR STRING; 8840.ENSAPLP00000019664; -.
DR Ensembl; ENSAPLT00000020347.1; ENSAPLP00000019664.1; ENSAPLG00000002713.2.
DR GeneTree; ENSGT00940000156612; -.
DR OMA; HTNEINL; -.
DR Proteomes; UP000016666; Chromosome 1.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0035102; C:PRC1 complex; IEA:Ensembl.
DR GO; GO:0001739; C:sex chromatin; IEA:Ensembl.
DR GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:1990830; P:cellular response to leukemia inhibitory factor; IEA:Ensembl.
DR GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR CDD; cd09577; SAM_Ph1_2_3; 1.
DR Gene3D; 3.30.60.160; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR012313; Znf_FCS.
DR InterPro; IPR038603; Znf_FCS_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF20; POLYHOMEOTIC-LIKE PROTEIN 1; 1.
DR Pfam; PF16616; PHC2_SAM_assoc; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF21319; zf-FCS_1; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS51024; ZF_FCS; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00367}.
FT DOMAIN 780..814
FT /note="FCS-type"
FT /evidence="ECO:0000259|PROSITE:PS51024"
FT DOMAIN 929..993
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 424..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 837..910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..644
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 648..662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..706
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 756..775
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 837..875
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 876..891
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 993 AA; 104792 MW; 758311853705E37D CRC64;
METESEQNSG SSSGSSSSGG STRPQISQMS LYERQAVQAL QALQRQPNAA QYFHQFMLQQ
QLNSAQLHSL AAVQQATIAA SRQASSPNTS TPQQTTTTQA SINLATTSAA QLISRSQSVS
SPSATTLTQS VLLGNTTSPP LNQSQAQMYL RPQLGNLLQV NRTLGRNVPL ASQLILMPNG
AVAAVQQEVP PTQSPGVHAD TDQVQNLAVR SQQTSSTNAQ LQSSAQKAAL PGNSQASCLP
QATSTGQTLA AAQVSSSSTG QSLNLSQGAA GSNGVSGGVV ASSGSQTSTG LSQTASAGAA
GSCQRKGTGV VQPLPVAAAQ AVTISQGSQT DTENAATKKG ETDSGGQQTV GMNLTRTATP
APSQTLISSA TYTQIQPHSL IQQQQQIHLQ KQVVIQQQIA IHHQQQFQHR QSQLLHTATH
LQLSQQQQQQ QSPSLTQQQQ QAQPPQQQAP PQNQQQAQTL VVQPMLQSQA QPVQLQQDSS
CQPATKSPVP IQSKSMVAPI KPPQLGPAKM SAAQQPPPHI PVQVVGTRQQ GSGQAQALGL
AQITAAVTTS RGMPAVVQPV SQGHAASPSS SAPPSSQEAP PLTTGVNLAQ VQGTTHMVKS
PASSPVVAQM PAAFYMQSVQ LPGKSQTLAV KRKAESEEEK EESASVTALL PARSSPVTDS
PKNMEEKNGF GDKSDPAAAA TPNTTSSEGA SVTPTSAPTP NLAMVSRQMG DSKPPQAIVK
PQILTHIIEG FVIQEGAEPF PVGSQLLKES EKPLQGGAPS GQSENLSSNS PGGDSASMEL
DKKANLLKCE YCGKYAPATQ FRGSKRFCSM TCAKRYNVSC SHQFRLQRKK MKEFQEANYA
RVRRRGSRRS SSEIARTKIQ GKRHRGQEDS SRGSDNSSYD EALSPTSPGP LSVRASHGER
DLANSSMAPP TPDLHGINPV FLSSNPSRWS VEEVYEFIAS LQGCQEIAEE FRSQEIDGQA
LLLLKEEHLM SAMNIKLGPA LKICAKINVL KET
//
