ID A0A493T6G9_ANAPP Unreviewed; 666 AA.
AC A0A493T6G9;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Amphiphysin {ECO:0000313|Ensembl:ENSAPLP00000021245.1};
GN Name=AMPH {ECO:0000313|Ensembl:ENSAPLP00000021245.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000021245.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000021245.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000021245.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A493T6G9; -.
DR Ensembl; ENSAPLT00000030911.1; ENSAPLP00000021245.1; ENSAPLG00000005709.2.
DR GeneTree; ENSGT00950000182882; -.
DR Proteomes; UP000016666; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR CDD; cd07611; BAR_Amphiphysin_I_II; 1.
DR CDD; cd12140; SH3_Amphiphysin_I; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR003005; Amphiphysin.
DR InterPro; IPR003017; Amphiphysin_1.
DR InterPro; IPR035470; Amphiphysin_I_SH3.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46514; AMPHIPHYSIN; 1.
DR PANTHER; PTHR46514:SF2; AMPHIPHYSIN; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR01251; AMPHIPHYSIN.
DR PRINTS; PR01252; AMPHIPHYSIN1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 24..240
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 593..666
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 244..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 17..59
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 152..186
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 287..309
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..438
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..462
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..540
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 73206 MW; 35166420B0F503E3 CRC64;
MADMKTGIFA KNVQKRLNRA QEKVLQKLGK ADETKDEQFE EYVQNFKRQE AEGSRLQREL
RAYLAAIKGM QDASKKLTES LHEVYEPDWY GREDVKMIGE KCDELWEDFH QKLVDGSLLT
LDTYLGQFPD IKTRIAKRSR KLVDYDSARH HLEALQSSKR KDEGRITKAE EEFQKAQKVF
EEFNTDLQEE LPSLWSRRVG FYVNTFKNVS SLEAKFHKEI ALLCHKLYEV MTKLGDQHAD
KAFTIQGAPS DSGPLRIAKT PSPPEEASPL PSPTASPNHM LAPASPAPAR PKSPTQLRKG
PPVPPLPKLT PTKELQQENI INLFDDNFVP EINVTTPSQT LPWDLWTTSS ELVQPASSTA
FNGFAQDAGA FTVQSNENVT ETLTEAEEAP PGEPKVEETS AAAAGEKEAI PAEPAKPAEQ
AAQTLEQVIS TSSPYDNIHK DSVEAGDKET TGVAEKEREV VTAVEGTAAA EDSLTVAAGA
GDGAVTEKEA VAEGEEPQGE EKEADASQEK VSSIPSVVIE PASNNEGEGE EHEVVMNESK
DVSAELDTQG TDSSPSETSQ VGSEQKPAEE IQAAPSQDQL VSSEDAASAM PPGFLFKVEV
LHDFEAANSD ELNLKRGDIV LVIPSETTAD QEAGWLTGIK ESEWLQYRDA NSYKGLFPEN
FTRHLE
//
