ID A0A493T703_ANAPP Unreviewed; 1305 AA.
AC A0A493T703;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Matrilin 2 {ECO:0000313|Ensembl:ENSAPLP00000021689.1};
GN Name=MATN2 {ECO:0000313|Ensembl:ENSAPLP00000021689.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000021689.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000021689.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000021689.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSAPLT00000035971.1; ENSAPLP00000021689.1; ENSAPLG00000014019.2.
DR GeneTree; ENSGT00940000158008; -.
DR Proteomes; UP000016666; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd01475; vWA_Matrilin; 1.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 17.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF35; MATRILIN-2; 1.
DR Pfam; PF14670; FXa_inhibition; 16.
DR Pfam; PF10393; Matrilin_ccoil; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 17.
DR SMART; SM00179; EGF_CA; 17.
DR SMART; SM01279; Matrilin_ccoil; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF58002; Chicken cartilage matrix protein; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 5.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS01186; EGF_2; 12.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 131..306
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 1017..1192
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 1202..1228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1305 AA; 147270 MW; 3140F5998BEA7DB2 CRC64;
MCAPASSPCV LELGQFELKE AGLWRGQIMQ PMFSSADVPE DPWGKTSCPA LKEARFSGSH
EKKEPQILHP GMSLYFLKMQ KMVACFFLLF GHMLLSTGSV MAKDLPGGHF TRRDVNSQSL
LENTCNRKRL DLVFIIDSSR SVRPYDFEKV KEFILTILQF LDISPDATRV GLIQYGSTVK
HEFSLKTFRR KQEIERAVRR MMHLATGTMT GLAIQYAVNI AFSESEGARP LSQNVPRIIM
IVTDGRPQDP VAEIAAKARN SGILIFAIGV GRVDMNTLKS IGSEPHEEHV FLVANFSQIE
TLTSAFQTKL CVPHMCSIVE HRCDHFCINT PGSYECRCKQ GYILNADQKT CSTQDLCAVE
KHACEQICVN TPGSYVCQCY EGYELDANGK NCIVVDYCAV DNQGCQHECV NTEDSYYCRC
YPGFILNPDK RTCRRPDYCA LQDHGCEQEC VNTDDSYFCQ CQEGFRLNPD KKTCKRVDHC
AESNHGCEHL CLNTDDSYVC QCFEGFVINE DLKTCTRVDY CALSDHGCEH LCINGDRSYT
CQCFEGYRLR NDGKTCKRKN ICKSVNHGCE HVCVSADNSY TCKCREGYIL REDGKTCRRQ
DICKSVSHGC EHICVNKDDS YACECHEGFL LREDGKTCRN KDICSSVAHG CEHVCVNADE
SYICQCYEGF ALREDGKTCR NKDVCNSVDH GCEHVCVNTD NSYICQCYEG FVLREDEKTC
KSKDICRSVN HGCEHLCVNN DDSYTCQCHD GFVLRQDGKT CRNKNLCKAI DHGCEHVCVN
TDDSYICKCH DGFLLREDGK TCKNKDVCNS INHGCEQVCV NTEDSYICRC HENFILKEDG
RTCRYKDVCK SVDHGCEHIC VNTDDSYICE CHEDFVLKED GKTCKSKNIC KTVNHGCEHV
CVPTGDSYVC QCHKGFILRR DRKTCRNKDL CKSIDHGCEH VCINNNNNSY SCQCHEGFVL
RQDGKTCRSK DVCKSVAHGC EHICVNNDDS YICKCQDGYV LKEDQKTCRR CTEGPVDLVF
VIDGSKSLGE DNFEIVKQFV SGILDTLEIS PKAARVGLLQ YSSEVRTEFT LRQFSSAKDM
KKAVSQMKYM GRGSMTGLAL KQMFQRSFTE TEGARPFSAN VPRIAIVFTD GRAQDEVSGW
AARAKQTGII IYAIGIGKAI EEELLEIASQ PSYKHLFYAE DFTALEDISE ELKVQICEAM
KNSAHQQDPS SGRLRKTGPQ SSGPESSTIT ITDVLACPNL AIHHKYHFED SHTHSTRTTA
KDKDQCKCEN LVTFQNYATS EVRKLTQRLE EMTKRMEDLE NRLKY
//
