ID A0A493T9R0_ANAPP Unreviewed; 391 AA.
AC A0A493T9R0;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Tetraspanin 4 {ECO:0000313|Ensembl:ENSAPLP00000022631.1};
GN Name=TSPAN4 {ECO:0000313|Ensembl:ENSAPLP00000022631.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000022631.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000022631.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000022631.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC {ECO:0000256|ARBA:ARBA00006840}.
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DR AlphaFoldDB; A0A493T9R0; -.
DR STRING; 8840.ENSAPLP00000022631; -.
DR Ensembl; ENSAPLT00000037712.1; ENSAPLP00000022631.1; ENSAPLG00000003602.2.
DR GeneTree; ENSGT00940000160434; -.
DR Proteomes; UP000016666; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03165; NET-5_like_LEL; 1.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR018503; Tetraspanin_CS.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; TETRASPANIN; 1.
DR PANTHER; PTHR19282:SF40; TETRASPANIN-4; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; Tetraspanin; 1.
DR PROSITE; PS00421; TM4_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 164..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 391 AA; 41485 MW; D2B6407BF3E0FECC CRC64;
MTPLPAPASG PAQGARPRGR AGRSPQGGSG WGPGGSGWAR GALSELLGLG QAGPGASPRG
SGRGQRGRRG GGRAVRRGAA LGCGSLGCQG PGGAGGGRPG VPAPCPPPAH PLPALPVALR
GMRSRAPAWR PPARRAPACF FVKVGALELK RCSMAHNCLQ CIKYLMFVFN LLFWLGGCGI
LGVGIWLAVT QGNFATLSSS FPSLSAANLL IVTGTFVMII GFVGCIGAIK ENKCLLLSFF
IMLLIIFLLE LTVVILFFVY TDKIDKYAQR DLKKGLHLYG TDGNIGLTNA WSIIQTDFRC
CGVSNYTDWF EVYNTTRVPD SCCLEFSENC GLHSPGTWWK APCYETVKIW LQENLLAVGI
FGLCTALVQI LGLTFAMTMY CQVVKADTYC A
//
