ID A0A493TCN9_ANAPP Unreviewed; 2555 AA.
AC A0A493TCN9;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Crystallin beta-gamma domain containing 3 {ECO:0000313|Ensembl:ENSAPLP00000023642.1};
GN Name=CRYBG3 {ECO:0000313|Ensembl:ENSAPLP00000023642.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000023642.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000023642.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000023642.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the beta/gamma-crystallin family.
CC {ECO:0000256|ARBA:ARBA00009646}.
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DR STRING; 8840.ENSAPLP00000023642; -.
DR Ensembl; ENSAPLT00000037234.1; ENSAPLP00000023642.1; ENSAPLG00000004185.2.
DR GeneTree; ENSGT00940000160816; -.
DR OMA; STENRNA; -.
DR Proteomes; UP000016666; Chromosome 1.
DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0051018; F:protein kinase A binding; IEA:Ensembl.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.60.20.10; Crystallins; 6.
DR InterPro; IPR001064; Beta/gamma_crystallin.
DR InterPro; IPR011024; G_crystallin-like.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR11818; BETA/GAMMA CRYSTALLIN; 1.
DR PANTHER; PTHR11818:SF38; VERY LARGE A-KINASE ANCHOR PROTEIN; 1.
DR Pfam; PF00030; Crystall; 4.
DR Pfam; PF00652; Ricin_B_lectin; 1.
DR PRINTS; PR01367; BGCRYSTALLIN.
DR SMART; SM00458; RICIN; 1.
DR SMART; SM00247; XTALbg; 5.
DR SUPFAM; SSF49695; gamma-Crystallin-like; 3.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50915; CRYSTALLIN_BETA_GAMMA; 5.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1919..1968
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 2064..2108
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 2109..2151
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 2199..2241
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT DOMAIN 2378..2419
FT /note="Beta/gamma crystallin 'Greek key'"
FT /evidence="ECO:0000259|PROSITE:PS50915"
FT REGION 70..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 133..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 687..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 832..879
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1224..1255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1268..1287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1421..1453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1666..1691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1714..1734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..296
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..431
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..703
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 856..879
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1232..1248
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1434..1453
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1718..1733
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2555 AA; 283633 MW; F1D20A8CDF146041 CRC64;
MGAAVSVGSG AEGEPTCHAV RAAALARLPL WKEWMAETSS EHKGSEAINL KNNQKESTTL
PALLKVCQNE EKNHSTEELN KSETQEELKK ANSLPSLTPG IKTADKDKQP REGFFQFLGS
LFNLTTKSSL VESKQSTFQD EPNRCEKDLQ NTNTPMEDMH PQHQKTEEPV YSTARMKEDS
VNKDDVIPNN VGKDCSKDIE KGQKRSADVR KKTQQKPQAP AVTYATYRGS ARIRQLMKNQ
SETAENGEES TENGNALMVK ENGEIQTTVS PKSGHLMKEN GEDEDKDHKD DVIVDSSNVK
IDLKKSSKTQ CCLRSNRHEV TPNASASPTE LSDEVDLKHT PALEATKVKR AYSLDSLLSS
SKDSEILTNS TSQITSSLKM GSVDKFMGKE DELLGEAETL FQMDKNATSN SDKEINCSKE
SDKESTKKMQ DDCLQSPKSN KTVNEELQAS KGEYCCNHQM NNHSELTSDV QELHSSSTTF
QQPADQHTDS ANKDSDPRKS NPQKIMAAAE REQNPQSFLA TIPLPFHEQI PTSLSMESRE
EKHIVTDNLT ASVLTIKSDE DIVMDQVTSN EELNKLGKPM QVLNEHQLIL AENSEDTATQ
QPALPCLEKI KVSSEVAVEN FADVLSCVHG RENGKSDFDE MTAPLSVTFE SSIETGDCCS
APLHPSCKSE NKTIVKRGVS LNNVRDTVSH SDHECEKSKS FEPVDTSLSE NSAPVHDLGT
VSLKTVQDIP AKAFFRLAED NTGKPAPCPL VNTDRTDNPI PAASKIDEAG MNEMTVVPSE
CKGYISEFSS PICKSQEKHL EDSHSALRSG GRPLANHSPV IAEKDVDVDI ISASSPSPED
RHISNSSRNE NSDKHRISST TFYSSSDNQG EIRSPSTNSE NCQIARCSAA AEQEGCVLLD
AESRRIIPED RMTETPLCSE DPRASCPVVS LEPEFTPAVL HHFDAEVDTW DFCIPKPTSP
TRGSKEASNL SISALETLGI AQENSNSSLL KAGDGAEEVS SAQQADSCVL VETVPSAICP
LKTLETASDS VHTEKVCRNA VEKVNLCNQA SSISESLSET DDQTAAAPRE SNELCFEKVW
KDTYGEGGQY TKFQDAALLF KKAEEIVDSV LHLAIEEIIA KQAVGVCHVC GSKDSLINTD
ILNDQKTGTM QLEEEEIQSA LHSLKHFNKR GSYSLMGNET YDTNNQDEKT PSYIPDKIDL
HSALTLKAKE IIDEVINSAK QKLISSQGQC SDSKRHSEKV KPKTEAETPK ILSLDSNLSA
RTQDIIKEPT ATGETQNVST SSENADCSDI PVVPNSMENS ADWPQRGEKI LNNAFTCQTN
GFLPTGSSAQ PESAPMILAK EEHDKKVYEH LAAAEMCGNA RLSATSRKSD VSLHLMTRDA
AVTEEMLLPL QLKDSCSNTD VPEYAVQPTV DINLLSFMPD EASSSMQSES KDKRSPQGSL
ESSAEDNTDE HSGREAAGVF AQVKATLEDS KVVENKEEQA EGASETTLFN IGLQTQFVAS
ELPVTGEHSE GKHCFKTVFA QNNENLKEVQ VKDQDMQRND QLEENGLDCS KGMKELVGLS
GSSPLIEQWE NSSFTIIYEG ALQTENKSVS TEDLETSSLS SSDLPLDSTD HLACERAKNK
HEPAYLYGKE NKLKEATESC SSESFLSVEA KRYRIYPFSL SPIYEDDSPQ EDLLSTDMSP
EGHPSGMSKD NADHASVLSL LQSVSERLQF TSQFSKEEEE GMEDEDEEQS SYEGNILDVE
REEQSLSSEW TGNLKTTLQS NDQNIYPFLE RSPFLSKEQL DSKEQPELVE EEASPRQTYC
KPVLQKADAA LKHAPTSVYY QYLKSATNYY SEKGTRFGSI LQDMLQPKIH WSQDHTMPKL
GELSANLIDR AGLKYNPRPG KIIIYDIHGD KSKQEVHSDV LDTTSWIFPI GALLRIIRGC
WIFYEKPKFQ GRKHVLEEGE TILDHLWDLP GVKHRRRNLT VGSIKHVTKD CSVPEIEFCL
GSGTGGLPIC IQSAVANLEE LDVEKNPYIS VKSGVWLGYS DYNYKGEMKI LEECNEPSEI
PSADVKSLRP LKMGGLKVQM PMNVKMIIYE KTHFGGWSKE LSENITSVLA LFDNKEDFKE
IGSMRIIGGV WVAYDKERYK GRQYLLEEGD YEDRHSWGGT DSVLLSFRFL QADFIESSVA
LFQSEDEDGK TLDIINEEIP DLEQAGFGPE TRSILVRSGV WVAYQQKHFC GEQYVLEKGK
YKCFFDWGGS SKIIMSIRPI KLEPLGTNEP PHWLKAFSNT HFQGACIDFT AEVSDFTSFI
PCSFKVLRGC WLLYYQGEIA DNHCVLEEGL YVDLTSCGCP TATIKSLKPI EYVFAEPSIS
LFALECCKGR ELHFTKPINS VLNEDLHFYT QSVWVRSGLW IAYEGCNFLG KQILLEPSEI
SNWSEYSGWK VIGSLRPMKQ PAVYLRIKNR AHGKYLTVSG SLADIRATSV CVSPYNGKNT
QLWHYCRGLF KSKANNACLD VIGGRDVPGA KVALWAEHGK ERQKWRLNED GTISSYLSDQ
LVLDIKGGNY YDKNHIIMNQ PVEDKHSQKW DIEIL
//
