ID A0A493TFE4_ANAPP Unreviewed; 1176 AA.
AC A0A493TFE4;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=NLR family CARD domain containing 3 {ECO:0000313|Ensembl:ENSAPLP00000024559.1};
GN Name=NLRC3 {ECO:0000313|Ensembl:ENSAPLP00000024559.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000024559.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000024559.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000024559.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A493TFE4; -.
DR Ensembl; ENSAPLT00000032835.1; ENSAPLP00000024559.1; ENSAPLG00000007304.2.
DR GeneTree; ENSGT00940000159861; -.
DR Proteomes; UP000016666; Chromosome 15.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd00116; LRR_RI; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR029495; NACHT-assoc.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF285; NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF13516; LRR_6; 11.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR SMART; SM01288; FISNA; 1.
DR SMART; SM00368; LRR_RI; 14.
DR SUPFAM; SSF52047; RNI-like; 2.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016666}.
FT DOMAIN 244..376
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REGION 42..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1176 AA; 127960 MW; 38DD9DA9C368BB7B CRC64;
MQQPGEQPWP GPHVGWGGYQ RCGFLGRAAL QFAYTAARQL CRDRKEDRAR PTAQEGARSE
TEQKQLGWHG TVGGGHRHHP WGAAPAPLWG PTAHSSSSGP RGAGAGAQLP FSDSSLSIRA
VRERSFGETS EQGHAGARRM LPPGLGASSL PPCSHGDVEK AARGREPMVQ KHLESLQSRY
GNGLETGPVP RLMNLLLVEG LTDIQQKEHD ILQIETTKGL RNVSKSIPLE KLFLPLSKVS
IPPRISVTVG VAGIGKSTLV KLFVSSWTKG EITRDIMLGL PLTFRELNTY EKLSAERLIR
LALPHATEPS CISAGAARVL LILDGLDEFK TPLDFSNTVV CTDPKKEIQV DNLITNIIRG
NLLQEASVWV TSRPTAASQI PGGLVDRMTE IRGFGAAEMK EFLDQMFLDN RDLSSQVLHH
IKANRSLHIM CTVPSFCRIS GSSIGYYLKT STDQSQEMTA APKTLSEIYS YYFKMALNSD
WPEKQRETLR IEQAVNNSKK ILGSLGRLAF YGLLKRKYVF YEQDMKTYGI DLSLLQSSLC
SRLLLKEEVQ SSTAYYFSHL TIQEFLAAIY YYTAAKRAIF DLFTENGMSW PKLGFLNHFK
SAVQRSLQAE DGQLDIFVRF LSGLLSPQVN KLLSGWLLAK DEHNSFRSQA ISFLQGCLNT
DYVISSRTVN TVHCLQEIQH MEIAKSVEEA MKNESLAGML TPVNCSVLAY LLQVSDVCVE
ETNLSNCLTY NVCKSLLPQL LFCHNLRLDN NQFKDNVMEL LGSVLSVKDC QIQKLSLAEN
QISNKGAKAL ARSLMVNRSL MVLDLRSNSI GPSGAKALAD ALKKNQVLLS LNLQHNVIKE
DGATFLAEAL LTNHKLTTLH LQKNSIGAQG ARKIAEALKR NCSLKELMLS SNSVGDNGSV
ALAEALKVNH SLQSLDLQSN SISSAGVAAL TAALCSNKGL VNLNLRENSI SKEGGPAIAR
ALRTNNTLRR LDLAANLLYD EGGKAIALAM KENRALTSLH LQWNFIQANA ATALAQALKS
NSSLASLDLQ ENAIGDEGMA ALSAALKVNT TLADLHLQVA SIGAAGAQAL AEALMVNKSL
QILDLRGNSI GVAGAKAMAN ALKVNRSLRR LNLQENSLGM DGAICIATAL KGNHGLTYVN
LQGNRIGQSG AKMISDAIRT NAPDCIVEVT FWAGSC
//
