ID A0A493TFU5_ANAPP Unreviewed; 555 AA.
AC A0A493TFU5;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Kelch-like protein 3 {ECO:0000256|ARBA:ARBA00023889};
GN Name=KLHL3 {ECO:0000313|Ensembl:ENSAPLP00000024719.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000024719.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000024719.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000024719.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the KLHL3 family.
CC {ECO:0000256|ARBA:ARBA00035639}.
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DR Ensembl; ENSAPLT00000026028.1; ENSAPLP00000023438.1; ENSAPLG00000000978.2.
DR Ensembl; ENSAPLT00000026148.1; ENSAPLP00000024719.1; ENSAPLG00000000978.2.
DR GeneTree; ENSGT00940000157891; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000016666; Chromosome 14.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd18513; BACK_KLHL3; 1.
DR CDD; cd18339; BTB_POZ_KLHL3; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR030578; KLHL3_BACK.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF475; RING CANAL KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 6.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR PRINTS; PR00501; KELCHREPEAT.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 18..85
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 555 AA; 61591 MW; 23C7940A1CAD82EE CRC64;
MRKAFKVMNE LRSKRLLCDV VIVAETVEME AHRVVLAACS PYFCAMFTGD MSESKAKKIE
IKDVDGQTLR KLIDYIYTAE IEVTEENVQV LLPAASLLQL MDVRKNCCDF LQSQLHPTNC
LGIRAFADVH ACTELLQQAN AYAEQHFPEV MLGEEFLSLS LDQVCSLISS DKLTVSSEEK
VFEAVISWIN YEKESRLEHM AKLMEHVRLP LLPRDYLVQT VEEEALIKNN NTCKDFLIEA
MKYHLLPLDQ RQLIKNPRTK PRTPVSLPKV MIVVGGQAPK AIRSVECYDF EEERWDQVAE
LPSRRCRAGV VFMAGNVYAV GGFNGSLRVR TVDVYDGVKD QWTSIASMQE RRSTLGAAVL
NDLLYAVGGF DGSTGLASVE AYSYKTNEWF FVAPMNTRRS SVGVGVVEGK LYAVGGYDGA
SRQCLSTVEQ YNPATNEWTY VADMSTRRSG AGVGVLSGLL YATGGHDGPL VRKSVEVYDP
GTNTWKQVAD MNMCRRNAGV CAVNGLLYVV GGDDGSCNLA SVEYYNPITD KWTLLPTSMS
TGRSYAGVAV IHKPL
//
