ID A0A493TI85_ANAPP Unreviewed; 781 AA.
AC A0A493TI85;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Protein tyrosine phosphatase domain containing 1 {ECO:0000313|Ensembl:ENSAPLP00000025549.1};
GN Name=PTPDC1 {ECO:0000313|Ensembl:ENSAPLP00000025549.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000025549.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000025549.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000025549.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A493TI85; -.
DR Ensembl; ENSAPLT00000019756.1; ENSAPLP00000025549.1; ENSAPLG00000013824.2.
DR GeneTree; ENSGT00390000004113; -.
DR OMA; CNERDPV; -.
DR Proteomes; UP000016666; Chromosome 13.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd14506; PTP_PTPDC1; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR049573; PTPDC1_PTP.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR23339:SF125; PROTEIN TYROSINE PHOSPHATASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR23339; TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE; 1.
DR Pfam; PF00782; DSPc; 1.
DR SMART; SM00195; DSPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666}.
FT DOMAIN 126..297
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 212..279
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 509..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..525
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..545
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 781 AA; 88969 MW; 087180D12EC018A7 CRC64;
MQGSPRRRSA ASIFSNFFQG RRHSSSDPLL RIIQRRRSSV VEVLSSSTQR VMVAISSLSP
EELDATFPEK KRGSRRPTAK YTKVGERLRH VIPGHMQCSM ACGGRACKYE NPARWSDQEQ
AIKGLYSSWI TDNILAMARP STELIEKYNI IEQFERCGIK TIINLQRPGE HASCGNPLEQ
ESGFTYLPEA FMEAGIYFYN FGWKDYGVAS LTTILDMVKV MAFALQEGRV AVHCHAGLGR
TGVLVACYLV FATRMTADQA ILFVRAKRPN SIQTRGQLLC IREFTQFLIP LRNVFACCEP
KAHTVTLSQY LTRQRHLLHG YESRHLKHVP KLIHLVCKLL LDLAENRQVI EAELLDVPDL
SAEIEKTVSQ LVSAQLDKEL ARQDSDMSDS SHTHSAPFET QDSLFSLAHE CDPLWKRRNI
DCLQPLTHVK RRLSYSESDL RRTEFLLEQA ETAWTVPAQI LQCNKLKQNR GEECSAKDDQ
KPQLDINKEA LVRNTCTIWS QTKFNLDGRK DGSSVHHRRN STKEVQRSRT FSSGLSSIHT
SRETRTPRQN FANEIGHRKE RMTNMYSRKV YVSEDSDSSS SSKVNFSIGC ESQGSKDLSE
AIPHIVLQSE LSLEGRRVLA AKALANINEF LEEDEVKQKV EMWQKELNSR DGAWDKICTE
RDPFILCSLM WSWIEQLKEP IISKDDIDML AKNCTESQDA LNLLRKEQCQ TILCILHCVV
NLQMLPADVE EALLARAIKA FTKTSLDSED GPYVYNTLKK VFKQTLEEKR KKLKEGTENP
S
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