ID A0A493TJQ6_ANAPP Unreviewed; 931 AA.
AC A0A493TJQ6;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
GN Name=KIF5B {ECO:0000313|Ensembl:ENSAPLP00000025963.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000025963.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000025963.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000025963.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC ECO:0000256|RuleBase:RU000394}.
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DR AlphaFoldDB; A0A493TJQ6; -.
DR Ensembl; ENSAPLT00000033827.1; ENSAPLP00000025963.1; ENSAPLG00000008099.2.
DR GeneTree; ENSGT00940000154801; -.
DR OMA; HIYAMEV; -.
DR Proteomes; UP000016666; Chromosome 2.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd01369; KISc_KHC_KIF5; 1.
DR Gene3D; 6.10.250.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 2.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47968; CENTROMERE PROTEIN E; 1.
DR PANTHER; PTHR47968:SF57; KINESIN FAMILY MEMBER 5C; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|RuleBase:RU000394};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000016666}.
FT DOMAIN 8..290
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 873..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 295..336
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 383..491
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 85..92
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 931 AA; 105962 MW; 7D9F71E21ACC97C4 CRC64;
MADPAECNIK VMCRFRPLNE SEVTRGDKYI AKFQGDDTVV IASKPYIFDR VFQSNTSQEQ
VYNDCAKKIV KDVLEGYNGT IFAYGQTSSG KTHTMEGKLH DPDGMGIIPR IVQDIFNYIY
SMDENLEFHI KGCTERFVCS PEEVMDTIDE GKSNRHVAVT NMNEHSSRSH SIFLINVKQE
NTQTEQKLSG KLYLVDLAGS EKVSKTGAEG AVLDEAKNIN KSLSALGNVI SALAESSTYV
PYRDSKMTRI LQDSLGGNCR TTIVICCSPS SYNESETKST LLFGQRAKTI KNTVCVNVEL
TAEQWKKKYE KEKEKNKTLR NTIQWLENEL NRWRNGETVP VDEQFDKEKA NLEAFAVDKD
ITIVNDKPAT TIGVTGNFTD AERRKCEEEI AKLYKQLDDK DEEINQQSQL VEKLKTQMLD
QEELLASTRR DQDNLQAELN RLQAENDASK EEVKEVLQAL EELAVNYDQK SQEVEDKAKE
YELLSDELNQ KSVTLASIDA ELQKLKEMTN HQKKRATEMM ASLLKDLAEI GIAVGNNDVK
QPEGTGMIDE EFTVARLYIS KMKSEVKTMV KRCKQLEGTQ AESNKKMEEN EKELAACQLR
ISQHEAKIKS LTEYLQNVEQ KKRQLEESVD SLNEELVQLR AQEKVHEMEK EHLNKVQTAN
EVKQAVEQQI QSHRETHQKQ ISSLRDEVDA KEKLITELQD QNQKMMLEQE RLRVEHEKLK
ATDQEKSRKL HELTVMQDRR EQARQDLKGL EETVAKELQT LHNLRKLFVQ DLATRVKKSA
EIDSDDTGGS AAQKQKISFL ENNLEQLTKV HKQLVRDNAD LRCELPKLEK RLRATAERVK
ALESALKEAK ENASRDRKRY QQEVDRIKEA VRSKNMARRG HSAQIAKPIR PGQHPAASPT
HPSAIRGGGA FTQNSQPVAL RGGGGRQDKV C
//
