ID   A0A493TKG1_ANAPP        Unreviewed;       666 AA.
AC   A0A493TKG1;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=BMP/retinoic acid inducible neural specific 2 {ECO:0000313|Ensembl:ENSAPLP00000026110.1};
GN   Name=BRINP2 {ECO:0000313|Ensembl:ENSAPLP00000026110.1};
OS   Anas platyrhynchos platyrhynchos (Northern mallard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Anas.
OX   NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000026110.1, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Proteomes:UP000016666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT   "A new Pekin duck reference genome.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000026110.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the BRINP family.
CC       {ECO:0000256|ARBA:ARBA00010360}.
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DR   AlphaFoldDB; A0A493TKG1; -.
DR   STRING; 8840.ENSAPLP00000026110; -.
DR   Ensembl; ENSAPLT00000046847.1; ENSAPLP00000026110.1; ENSAPLG00000019011.1.
DR   GeneTree; ENSGT00940000160314; -.
DR   OMA; LSACCRW; -.
DR   Proteomes; UP000016666; Unassembled WGS sequence.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:InterPro.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:InterPro.
DR   InterPro; IPR033237; BRINP.
DR   InterPro; IPR020864; MACPF.
DR   PANTHER; PTHR15564:SF8; BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 2; 1.
DR   PANTHER; PTHR15564; MACPF DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF19052; BRINP; 1.
DR   Pfam; PF01823; MACPF; 1.
DR   SMART; SM00457; MACPF; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00022810};
KW   Growth arrest {ECO:0000256|ARBA:ARBA00022810};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           16..666
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5019712918"
FT   DOMAIN          65..250
FT                   /note="MACPF"
FT                   /evidence="ECO:0000259|SMART:SM00457"
SQ   SEQUENCE   666 AA;  75560 MW;  5BFFD6C2046FFA87 CRC64;
     VWWLLLQGIK HAAGAASPSS PSSSSPSRAP LDWLLTDRGP FYRAQEYVDF TERYRQGFTT
     RYRIYREFAR WKVNNLALER KDFFSLPLPL APEFIRNIRL LGRRPSLQQV TDSIIKKYGT
     HFLLAATLGG EESLTIFVDK RKLSRRAEPA GAGNSSAVSL ETLHQLAASY FIDRESTLRR
     LHHIQIATAA IKVTETRTGP LGCSNYDNLD SVSSVLVQSP ENKVQLQGLQ TVLPPHLRER
     FVAAALSYIA CGSAGELLCR RSDCRCQCQP AFPHCNCPEA DVQALEGSLA QLHRAWESHH
     GQFEESEEFQ ALVKRLPGDR FLNRTAISHF WAMDLDVQHR YQQLGTSLKL LARKTHRIIR
     RLFNLSKRCH RQPRFKLPKE RSLPYWWSRA QSLLYCSETT VPGTFLEESH SCTCPSEQPS
     CQGSIPCALG EGTACASCAE DNTTRCGACN QGYVLAQGSC RPEVADSLEH YLGLETDLQD
     LELKYLLQKR DSRIEVHSIF ISNDMRLGSW FDPSWRKRML LTLKSNKYKP GLVHVMLALS
     LQICLTKNST LEPVMAIYVN PFGGSHSESW FVPVNEGSFP DWERTNVDAS AQCQNWTLTL
     GNKWKTFFET VHVYLRSRIK SLDDSSNETI YYEPLEMADP SKNLGYMKIN SLQVFGYSLP
     FEPDAI
//