ID A0A493TLW8_ANAPP Unreviewed; 446 AA.
AC A0A493TLW8;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=EGF like repeats and discoidin domains 3 {ECO:0000313|Ensembl:ENSAPLP00000026839.1};
GN Name=EDIL3 {ECO:0000313|Ensembl:ENSAPLP00000026839.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000026839.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000026839.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000026839.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; A0A493TLW8; -.
DR Ensembl; ENSAPLT00000019853.1; ENSAPLP00000026839.1; ENSAPLG00000016364.2.
DR GeneTree; ENSGT00940000158144; -.
DR Proteomes; UP000016666; Chromosome Z.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 3.
DR CDD; cd00057; FA58C; 2.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR46806:SF10; EGF-LIKE REPEAT AND DISCOIDIN I-LIKE DOMAIN-CONTAINING PROTEIN 3 PRECURSOR; 1.
DR PANTHER; PTHR46806; F5/8 TYPE C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF00754; F5_F8_type_C; 2.
DR Pfam; PF12661; hEGF; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM00231; FA58C; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01285; FA58C_1; 2.
DR PROSITE; PS01286; FA58C_2; 1.
DR PROSITE; PS50022; FA58C_3; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..446
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019843631"
FT DOMAIN 19..57
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 71..114
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 116..152
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 155..311
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 316..416
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DISULFID 28..45
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 47..56
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 104..113
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 142..151
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 446 AA; 49567 MW; 0060DDB01422305D CRC64;
MSRTVLAWLA LCGSLALARG DLCDSNPCRN GGICLSGLND DFYSCECPEG FTDPNCSSVV
EVASIEEEPT SAGPCLPNPC HNGGMCEISE AYRGDTFIGY VCKCPEGFNG IHCQHNVNEC
EAEPCKNGGI CTDLVANYSC ECPGEFMGRN CQQRCSGPLG IEGGIVSNQQ ITASSTHRAL
FGLQKWYPYY ARLNKKGLVN AWTAAENDRW PWIQINLQKK MRVTGVITQG AKRIGSPEYV
KSYKIAYSND GKSWTMYKVK GTNEDMVFRG NVDNNTPYAN SFTPPIKSQY VRLYPQVCRR
HCTLRMELLG CELSGCSEPL GMKSGHIQDY QISASSVFRT LNMDMFAWEP RKARLDKQGK
VNAWTSGHND QSQWLQVDLL VPTKVTGIIT QGAKDFGHVQ FVGSYKLAYS NDGEHWIIYQ
DEKQKKDKMT KAIQSLSEHS KNASCQ
//
