ID   A0A493TMZ3_ANAPP        Unreviewed;       904 AA.
AC   A0A493TMZ3;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=NEDD4-binding protein 1 {ECO:0000256|ARBA:ARBA00039336};
GN   Name=N4BP1 {ECO:0000313|Ensembl:ENSAPLP00000027252.1};
OS   Anas platyrhynchos platyrhynchos (Northern mallard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Anas.
OX   NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000027252.1, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Ensembl:ENSAPLP00000027252.1, ECO:0000313|Proteomes:UP000016666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT   "A new Pekin duck reference genome.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000027252.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus, PML body
CC       {ECO:0000256|ARBA:ARBA00004322}. Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the N4BP1 family.
CC       {ECO:0000256|ARBA:ARBA00038274}.
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DR   AlphaFoldDB; A0A493TMZ3; -.
DR   Ensembl; ENSAPLT00000019234.1; ENSAPLP00000027252.1; ENSAPLG00000012344.2.
DR   GeneTree; ENSGT00940000158682; -.
DR   Proteomes; UP000016666; Chromosome 12.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   CDD; cd22476; KH-I_N4BP1; 1.
DR   CDD; cd09032; KH-I_N4BP1_like_rpt1; 1.
DR   CDD; cd18728; PIN_N4BP1-like; 1.
DR   Gene3D; 3.40.50.11980; -; 1.
DR   InterPro; IPR021869; RNase_Zc3h12_NYN.
DR   PANTHER; PTHR12876; N4BP1-RELATED; 1.
DR   PANTHER; PTHR12876:SF26; NEDD4-BINDING PROTEIN 1; 1.
DR   Pfam; PF11977; RNase_Zc3h12a; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666}.
FT   DOMAIN          632..784
FT                   /note="RNase NYN"
FT                   /evidence="ECO:0000259|Pfam:PF11977"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          240..261
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          413..480
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          518..603
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        422..454
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        455..473
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        521..541
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        549..577
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        578..598
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   904 AA;  100847 MW;  702F2839673A7430 CRC64;
     MATRCGAARG SRPGPGPDEF TVPAEKSRLL EGSRGRIEGL FEVRLAVLGA QEDWRAALSP
     PGRPPAAARI WVQLAGGGKA VRCAKEYIKG LCEPELEEKQ YYPKDMHCIF VGAQSVFLNS
     LIQDTCADIT VLEIGLLIIK GGAEAVVMAQ SHVQQFVNLF ENNESLPSDN ESEIKKQFRQ
     FVEAHADKYT MDLLILPSSL KRELLSLTQT ECCEAESNIV DLTGSESPTE FLQDKASKVN
     VTNRDGRTGG EEARNNAGTP VTELTKQMDT VFSDAPETSF VPINVVPSLE AGVSKERQSC
     KRRSSDVEER LPKKQFSLEN DQEVKSTSHS DPSGKDVVID LLSDSCGELD DPNYFIKEDD
     DISEEMEYKI LVNFFRTMGY SQSIVEKVIG ILGQSVEPLT LLEEIEKENL KFQKEHELSS
     QKPRTINPPL GSNANNSQKT EDKGISSSKN VLKSGHTSKE TKNEHHNIRD VPSTQADGED
     QMHITICKPV SPETDGVITF SPIQRGVPKD VDFVARGSSD MQRVSAKTKT TAQQKSAGLS
     AVQNPHPVAE DQLGQSSSSQ VRSRNQHPLQ TSDFEKPTTA HVKIHHSSPD RETVGPHRRN
     IDPSVTGVQR FMESLKKPYR LELKNEPGNP YLKHIVIDGS NVAMSHGLKK FFSCRGIAIA
     VDYFWKRGHR NITVFVPQWR TRRDPYITEQ DFLTQLQDVG ILSLTPARMV LGARIAAHDD
     RFLLHLADKT GGVIVTNDNF REFVTESFAW REIIQKRLLQ YTFAGDIFMV PDDPLGRNGP
     RLDDFLRSEG CSRDFLSAQR ALQNSGQYSS ETPFFVQVPK PTSSSRQPKN RAHSDCSSTW
     LPLETNMNAC LAIPPQRSAS ETVQLREALR KIFPDYEQRQ KIDQILADHP FMRDLNALSA
     MVLD
//