ID A0A493TPL8_ANAPP Unreviewed; 302 AA.
AC A0A493TPL8;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta {ECO:0000313|Ensembl:ENSAPLP00000027813.1};
GN Name=YWHAB {ECO:0000313|Ensembl:ENSAPLP00000027813.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000027813.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000027813.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000027813.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 14-3-3 family.
CC {ECO:0000256|ARBA:ARBA00006141, ECO:0000256|RuleBase:RU003466}.
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DR AlphaFoldDB; A0A493TPL8; -.
DR STRING; 8840.ENSAPLP00000027813; -.
DR Ensembl; ENSAPLT00000029802.1; ENSAPLP00000027813.1; ENSAPLG00000018025.1.
DR GeneTree; ENSGT01090000260040; -.
DR OMA; EQHVTII; -.
DR Proteomes; UP000016666; Chromosome 21.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0042826; F:histone deacetylase binding; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0050815; F:phosphoserine residue binding; IEA:Ensembl.
DR GO; GO:0019904; F:protein domain specific binding; IEA:Ensembl.
DR GO; GO:0004860; F:protein kinase inhibitor activity; IEA:Ensembl.
DR GO; GO:0051220; P:cytoplasmic sequestering of protein; IEA:Ensembl.
DR GO; GO:0045744; P:negative regulation of G protein-coupled receptor signaling pathway; IEA:Ensembl.
DR GO; GO:0035308; P:negative regulation of protein dephosphorylation; IEA:Ensembl.
DR GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR CDD; cd10022; 14-3-3_beta_zeta; 1.
DR Gene3D; 1.20.190.20; 14-3-3 domain; 1.
DR InterPro; IPR000308; 14-3-3.
DR InterPro; IPR023409; 14-3-3_CS.
DR InterPro; IPR036815; 14-3-3_dom_sf.
DR InterPro; IPR023410; 14-3-3_domain.
DR PANTHER; PTHR18860; 14-3-3 PROTEIN; 1.
DR PANTHER; PTHR18860:SF28; 14-3-3 PROTEIN BETA_ALPHA; 1.
DR Pfam; PF00244; 14-3-3; 1.
DR PRINTS; PR00305; 1433ZETA.
DR SMART; SM00101; 14_3_3; 1.
DR SUPFAM; SSF48445; 14-3-3 protein; 1.
DR PROSITE; PS00796; 1433_1; 1.
DR PROSITE; PS00797; 1433_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666}.
FT DOMAIN 61..300
FT /note="14-3-3"
FT /evidence="ECO:0000259|SMART:SM00101"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 123..161
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 302 AA; 33973 MW; 99F6F30DFAEB1E74 CRC64;
MGRRLPPQVP PPGAGRGVAS GPEAGPQRRR VCVCLCVRSR RSARRDPGRG AAAPARIVMD
KSELVQKAKL AEQAERYDDM AAAMKAVTEQ GHELSNEERN LLSVAYKNVV GARRSSWRVI
SSIEQKTERN EKKQQMGREY REKIEAELQD ICNDVLELLD KYLIVNATQP ESKVFYLKMK
GDYYRYLSEV ASGDNKQTTV ANSQQAYQEA FEISKKEMQP THPIRLGLAL NFSVFYYEIL
NSPEKACNLA KTAFDEAIAE LDTLNEESYK DSTLIMQLLR DNLTLWTSEN QGDEGDAGEG
EN
//
