ID   A0A493TU78_ANAPP        Unreviewed;       636 AA.
AC   A0A493TU78;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732};
OS   Anas platyrhynchos platyrhynchos (Northern mallard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Anas.
OX   NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000029105.1, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Ensembl:ENSAPLP00000029105.1, ECO:0000313|Proteomes:UP000016666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT   "A new Pekin duck reference genome.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000029105.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC       2.A.22) family. {ECO:0000256|RuleBase:RU003732}.
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DR   AlphaFoldDB; A0A493TU78; -.
DR   STRING; 8840.ENSAPLP00000029105; -.
DR   Ensembl; ENSAPLT00000046576.1; ENSAPLP00000029105.1; ENSAPLG00000030026.1.
DR   GeneTree; ENSGT00940000164714; -.
DR   OMA; HHLEYMT; -.
DR   Proteomes; UP000016666; Chromosome 13.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   CDD; cd11509; SLC6sbd_CT1; 1.
DR   InterPro; IPR000175; Na/ntran_symport.
DR   InterPro; IPR037272; SNS_sf.
DR   PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR   PANTHER; PTHR11616:SF126; TRANSPORTER; 1.
DR   Pfam; PF00209; SNF; 1.
DR   PRINTS; PR00176; NANEUSMPORT.
DR   SUPFAM; SSF161070; SNF-like; 1.
DR   PROSITE; PS00610; NA_NEUROTRAN_SYMP_1; 1.
DR   PROSITE; PS00754; NA_NEUROTRAN_SYMP_2; 1.
DR   PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW   Symport {ECO:0000256|RuleBase:RU003732};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003732};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003732}.
FT   TRANSMEM        55..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        85..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        127..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        237..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        270..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        317..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        346..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        449..474
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        480..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        525..544
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        564..585
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   636 AA;  70204 MW;  20E43473F10C5986 CRC64;
     MGARAAGVGP PVPAEGAEPP AAGEERAVTA PLVGPPGPPK AAAPERETWT RQMDFIMSCV
     GFAVGLGNVW RFPYLCYKNG GGVFLIPYLL IVFVGGIPVF FLEVALGQFM KQGGIAAWNI
     APPFKGLGLA SMVIVFFCNS YYIMILVWGL FYLVHSLTDT LPWATCGHAW NTEQCAEFFH
     LELCRNASTN ASAAAAAGAL NFSCTDLANK RSPVIEFWEN KVLRLSGDLS EPGEMNWQMI
     LCLVTTWVVV YFCIWKGVKS TGKIVYFTAL FPYVVLILLL VHGVTLPGAL GGIVYYLKPD
     WSKLAEAQVW IDAGTQIFFS YAIGLGALTA LGSYNRFHNN CYRDAYILAV INSSTSFFAG
     FVVFSVLGFM ASEQGVDISK VAESGPGLAF IAYPKAVTLM PLSPLWATLF FFMLLVLGLD
     SQFVGVEGFI TGILDLFPQP GAGSLRRELT AALCCVVCCL IDLSMVTQGG MYVFQLFDYY
     SASGITLLWQ AFWECVVIAW VYGADRFMDD VARMIGYRPL PFMKWCWAVV TPLVCVGIFV
     FHVVNYKPLT YNKTYVYPWW GDAIGWVLAL SSMLCIPCTV LYKLLRCKGS LRERWQLLTT
     PIWGHHHLEY LTPEAEAKLL APEPPKEKTT LFETVI
//