ID A0A493TUF7_ANAPP Unreviewed; 329 AA.
AC A0A493TUF7;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=palmitoyl-protein hydrolase {ECO:0000256|ARBA:ARBA00012423};
DE EC=3.1.2.22 {ECO:0000256|ARBA:ARBA00012423};
GN Name=LYPLAL1 {ECO:0000313|Ensembl:ENSAPLP00000029533.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000029533.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000029533.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000029533.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 2
CC family. {ECO:0000256|ARBA:ARBA00006499}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A493TUF7; -.
DR STRING; 8840.ENSAPLP00000029533; -.
DR Ensembl; ENSAPLT00000035482.1; ENSAPLP00000029533.1; ENSAPLG00000019149.1.
DR GeneTree; ENSGT00940000159171; -.
DR OMA; LEYPHIK; -.
DR Proteomes; UP000016666; Chromosome 3.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; IEA:Ensembl.
DR GO; GO:0160049; P:negative regulation of cGAS/STING signaling pathway; IEA:Ensembl.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR003140; PLipase/COase/thioEstase.
DR PANTHER; PTHR10655:SF71; LYSOPHOSPHOLIPASE-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR10655; LYSOPHOSPHOLIPASE-RELATED; 1.
DR Pfam; PF02230; Abhydrolase_2; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000016666}.
FT DOMAIN 103..316
FT /note="Phospholipase/carboxylesterase/thioesterase"
FT /evidence="ECO:0000259|Pfam:PF02230"
FT REGION 37..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 36341 MW; 282523D20FA47841 CRC64;
MYVCIYLCIY LFILNVKPPA FQTRLQRLRS VSAVAPQPGC ARRPRDAPLP AGRYEEPAGA
GSSCWAGPGP ARGRLWAGPS RAEGGRRRRR AAGMAAPGAL QRSVVLPAGR HSASLIFLHG
SGDTGQGART WIKQILNQDM AFQHIKVIYP TAPARPYTPM KGAFSTVWFD RYKISNECPE
HIESIDSMCR GLTDLINDEV KNGIAKNRIL IGGFSMGGGM AMHLAYRFHQ DLAGVFALSS
FLNKDSAVYQ TLKKTKSILP ELFQCHGTAD ELVLYSWGEE TNKMLKSLGV STSLHTFPNL
NHELNRTEIE KLKTWILNKL PIEAAETNE
//
