ID A0A493TY64_ANAPP Unreviewed; 1108 AA.
AC A0A493TY64;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=MLLT10 histone lysine methyltransferase DOT1L cofactor {ECO:0000313|Ensembl:ENSAPLP00000030801.1};
GN Name=MLLT10 {ECO:0000313|Ensembl:ENSAPLP00000030801.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000030801.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000030801.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000030801.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A493TY64; -.
DR Ensembl; ENSAPLT00000041215.1; ENSAPLP00000030801.1; ENSAPLG00000016316.2.
DR GeneTree; ENSGT00940000157711; -.
DR Proteomes; UP000016666; Chromosome 2.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd20901; CC_AF10; 1.
DR CDD; cd15708; ePHD_AF10; 1.
DR CDD; cd15574; PHD_AF10_AF17; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR049773; AF10-like_CC.
DR InterPro; IPR049781; AF10/AF17_PHD.
DR InterPro; IPR049775; AF10_ePHD.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR PANTHER; PTHR13793:SF93; PROTEIN AF-10; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 98..150
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 155..274
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 210..273
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 352..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 485..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 696..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 839..901
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 776..813
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 290..309
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 400..433
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1108 AA; 116432 MW; 3156F4796A3D9473 CRC64;
MSRVTSRVGA GRMSATSPSP HGGEGGSNRP GLGRAGRAAP RGPSRAAPRA CGARPGAAAM
ARPGGDAEWQ HAEMVSSEPL LLPVSLEGEF SSSMKEMIGG CCVCSDERGW AENPLVYCDG
HGCNVAVHQA CYGIVQVPTG PWFCRKCESQ ERAARVRCEL CPHKDGALKR TDNGGWAHVV
CALYIPEVQF ANVSTMEPIV LQSVPHDRYN KTCYICDEQG RESKAASGAC MTCNKHGCRQ
AFHVTCAQFA GLLCEEEGNG ADNVQYCGYC KYHFSKLKFG LAHRRSEKLH SMGQKYKEKD
KHKQKYKKQS ESSPSLVPSL TVTTEKTYTS TSNNSMSGSL KRLEDTTARF TNANFQEVST
HVSSGKDSSE ARGSESKGKK SAGHSSGQRG RKPGAGRNPG TTVTAASPFQ QGSFLGTPSS
IKSSSGSSVQ SPQDFLSFTE TDLRNDSFTH SQQTSSTKDV HKGETGSQEG AVNCFTSLIG
LPSSSAVSQS KNFDSSPGDI GNSSLTSTAY KRAQTSGIEE ETVTEKKRKG NKQSKHGPGR
PKGNKSQESI SHLSVSSASP TSSVASAAGS VTSSGLQKSP TLLRNGSLQS LSVGSSPVGS
GIFSSNDVAV SFPNAVSGSG SSTPVSSSHL PQQASGHLQQ VGALSPSTAP SITTVVAATQ
ANTLPGSSLS LPPSHMYGNR LNPNSAMATL IAQTENSQAD QDLGDNSRSL VGRGGSPRGS
LSPRSPVSSL QIRYDQSGNN CGENLPPVAA SIEQLLERQW SEGQQFLLEQ GTPSDILGML
KSLHQLQVEN RRLEEQIKNL TAKKERLQLL NAQLSVPFPT ITSNPSPSHQ VHAFPVQAAP
STDSLNSSKS PHLGNSFLPD NSLPVLNQEI TSSGQSTSSS SALSTPPPAG QSPAQQGSGV
TGVQQVNGVT VGALASGMQT VTSTIPAVPG VGGIIGALPA SQLAINGIVG ALNGVIQTPA
TISQNPSPLT HATVPPNATH PLPTTLNNSA SGLGLLPDQQ RQLLLHQQHQ QFQQLLSTQQ
LTSEQHQALL YQLVQQQHHH QHHHQSEVQQ LQITGGAQIP INNLLSGTQA SPLNAASTNP
FLTIHGDNAA QKVTRLSDKT GPVASEKS
//
