ID A0A494B9B0_MOUSE Unreviewed; 174 AA.
AC A0A494B9B0;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Aspartoacylase (aminoacylase) 3 {ECO:0000313|Ensembl:ENSMUSP00000157563.2};
DE Flags: Fragment;
GN Name=Acy3 {ECO:0000313|Ensembl:ENSMUSP00000157563.2,
GN ECO:0000313|MGI:MGI:1918920};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000157563.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000157563.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000157563.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000157563.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000157563.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A494B9B0; -.
DR SMR; A0A494B9B0; -.
DR jPOST; A0A494B9B0; -.
DR Antibodypedia; 30490; 350 antibodies from 25 providers.
DR Ensembl; ENSMUST00000236224.2; ENSMUSP00000157563.2; ENSMUSG00000024866.11.
DR AGR; MGI:1918920; -.
DR MGI; MGI:1918920; Acy3.
DR VEuPathDB; HostDB:ENSMUSG00000024866; -.
DR GeneTree; ENSGT00390000001189; -.
DR OMA; AMHLCHH; -.
DR Proteomes; UP000000589; Chromosome 19.
DR Bgee; ENSMUSG00000024866; Expressed in right kidney and 114 other cell types or tissues.
DR ExpressionAtlas; A0A494B9B0; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd06909; M14_ASPA; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR007036; Aste_AspA.
DR PANTHER; PTHR15162; ASPARTOACYLASE; 1.
DR PANTHER; PTHR15162:SF5; N-ACYL-AROMATIC-L-AMINO ACID AMIDOHYDROLASE (CARBOXYLATE-FORMING); 1.
DR Pfam; PF04952; AstE_AspA; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 1: Evidence at protein level;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Proteomics identification {ECO:0007829|MaxQB:A0A494B9B0,
KW ECO:0007829|PeptideAtlas:A0A494B9B0};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT NON_TER 174
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000157563.2"
SQ SEQUENCE 174 AA; 19060 MW; 155D57D5407DEEC1 CRC64;
MSSLPGSREP LLRVAVTGGT HGNEMCGVYL ARYWLQNPGE LQRPSFSAMP VLANPAATAA
CCRYLDRDLN RSCTLTFLGS TATPDDPYEV KRARELNQLL GPKGTGQAFD FTLDLHNTTA
NTGVCLISES NISFNLHLCH YLQRQNPGMP CRLFLYEPAG TETFSVESIS KNGI
//
