ID   A0A495ACN4_9BACI        Unreviewed;       327 AA.
AC   A0A495ACN4;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   24-JAN-2024, entry version 9.
DE   SubName: Full=Alpha-ketoacid dehydrogenase subunit beta {ECO:0000313|EMBL:RKQ37737.1};
GN   ORFNames=D8M06_02740 {ECO:0000313|EMBL:RKQ37737.1};
OS   Oceanobacillus halophilus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX   NCBI_TaxID=930130 {ECO:0000313|EMBL:RKQ37737.1, ECO:0000313|Proteomes:UP000269301};
RN   [1] {ECO:0000313|EMBL:RKQ37737.1, ECO:0000313|Proteomes:UP000269301}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23996 {ECO:0000313|EMBL:RKQ37737.1,
RC   ECO:0000313|Proteomes:UP000269301};
RX   PubMed=26869142; DOI=.1099/ijsem.0.000952;
RA   Amoozegar M.A., Bagheri M., Makhdoumi A., Nikou M.M., Fazeli S.A.S.,
RA   Schumann P., Sproer C., Sanchez-Porro C., Ventosa A.;
RT   "Oceanobacillus halophilus sp. nov., a novel moderately halophilic
RT   bacterium from a hypersaline lake.";
RL   Int. J. Syst. Evol. Microbiol. 66:1317-1322(2016).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RKQ37737.1}.
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DR   EMBL; RBZP01000001; RKQ37737.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A495ACN4; -.
DR   OrthoDB; 9771835at2; -.
DR   Proteomes; UP000269301; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000269301}.
FT   DOMAIN          4..179
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   327 AA;  36000 MW;  F569CD6BA7537D0A CRC64;
     MAVMSYIQAV TTALREEMLR DEKVFILGED VGKKGGVFRA TEGLFDEFGE YRVLDTPLTE
     SAIAGVGIGA AMYGMRPVAE MQFADFIMPA VNQIISEAAK TRYRSNNDWN VPITIRAPYG
     GGVHGALYHS QSVESVFANQ PGLKIVMPST PYDVKGLLKA AIRDNDPVLF FEHKRAYRLL
     KEDVPEEDYV LPIGKADVKR EGSDITVITY GLCVHFALQA AEKLAEEGID AHILDLRTVY
     PLDKAAIIEA ASKTGKVLLI TEDNKEGSII GEVAAIIAEN CLFDLDAPIM RLAGPDVPAM
     PYAPTMERYF MVNPEKCEKA MRDLAEF
//