ID A0A495JC39_9ACTN Unreviewed; 550 AA.
AC A0A495JC39;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=ATP-dependent DNA helicase RecQ {ECO:0000313|EMBL:RKR86291.1};
GN ORFNames=BDK92_0515 {ECO:0000313|EMBL:RKR86291.1};
OS Micromonospora pisi.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=589240 {ECO:0000313|EMBL:RKR86291.1, ECO:0000313|Proteomes:UP000277671};
RN [1] {ECO:0000313|EMBL:RKR86291.1, ECO:0000313|Proteomes:UP000277671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45175 {ECO:0000313|EMBL:RKR86291.1,
RC ECO:0000313|Proteomes:UP000277671};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKR86291.1}.
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DR EMBL; RBKT01000001; RKR86291.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495JC39; -.
DR OrthoDB; 9760034at2; -.
DR Proteomes; UP000277671; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:RKR86291.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000277671}.
FT DOMAIN 32..203
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 230..382
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 550 AA; 59499 MW; B9AE862CAC8C8407 CRC64;
MKLPTLHSTR LRRVARQHFG WGSLRPGQLA AMRALLKRRD ALVVLPTGAG KSAIYQVPAA
LLPGPTVVVS PLLALQEDQI RALNDRGDTR LRAVRVSSAE TPNQQAAALR EIATGAARFL
FITPEQLSNP ECLAKVRALR PALVAVDEAH CISAWGNDFR PDYLALGQLI RGLGRPPVVA
LTATASPPVR EDIVARLGLE NPRTVVAGLD RPNLFLEVAH CPTEEYRWRR LLRLLDTDQR
PGIVYVPTRR AAEELAARLT EAGHDAAYYH GGMPAGARTE LHERFLDDQV PIMVATSAFG
MGIDKPNIRW VAHLALPDSP DSYLQEIGRA GRDGSPAHAL LLWRAEDVGL QRFFTGGTPD
ADELAELAAV LRTGPVTRAA LRERTGWGSR KLGQLLALLE RVGAAGTTGP KQRVSSPRYA
PEPAEAARAA VAEAERQQAV QRSRTDMMRA FAEATGCRSQ PLLAYFGEQL ESTCGHCDSC
HAGTSTAGDG ASGPFPVHST VRHAEWGPGL VLSYEDDRMT VLFENVGYKT LSVPVVSEQG
LLTGDGSRNS
//
