ID A0A495JVC7_9ACTN Unreviewed; 1178 AA.
AC A0A495JVC7;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Amino acid adenylation domain-containing protein {ECO:0000313|EMBL:RKR92252.1};
GN ORFNames=BDK92_6690 {ECO:0000313|EMBL:RKR92252.1};
OS Micromonospora pisi.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=589240 {ECO:0000313|EMBL:RKR92252.1, ECO:0000313|Proteomes:UP000277671};
RN [1] {ECO:0000313|EMBL:RKR92252.1, ECO:0000313|Proteomes:UP000277671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45175 {ECO:0000313|EMBL:RKR92252.1,
RC ECO:0000313|Proteomes:UP000277671};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKR92252.1}.
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DR EMBL; RBKT01000001; RKR92252.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495JVC7; -.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000277671; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR CDD; cd12116; A_NRPS_Ta1_like; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000277671}.
FT DOMAIN 1060..1135
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1178 AA; 125850 MW; DD546F86BDD1F519 CRC64;
MPSTADPDAG TPTTAQPPDV RGSVVGLSPQ RQALLARRLA QRGLASVTEP LIARLPRTGP
EQRFTCSSGQ QRMWLANQFD PADPSFHVSI SQRMRGDLDV GALRQALADL VTRHEILRTV
YVGVDGTPHQ IVRPPAPVPM GEVDLRELPV VDREPRARSL ARRAFAVPFD LATGPVLRAV
LYRLADDDRV LLMTSHHIAI DGWSIGNALR ELAALYRWRL TTPAGPSAAG PPPLPELTIQ
YVDYAHWQHE SLADGELADG LDFWRRQLAA PRASAELPIA HRPEPDATSD STSTGGAGTG
TGTGTGTGGK VGLMIGPELL DRLRTAAGAT RGTTPFVTLL TGFKALLARY LGQPDVTVGT
LVAARTHVEL EPLIGYFANP VALRTRLDPE LTFAEAVSRV RRTVIDGFAY QSVPFDRVVQ
ELAPRREAGR HPFFQAALIL HNFSAGTPED WPGLDVRWWN SELDDMLFDL TLVAVPQPDG
GLEATFSYRT DVFDAADIGR LAEGFTELLA GIAADPGQRL GDLPLLTPAQ RQWLLVDRQG
PVREPTPQTA TFPALWARSR DRHPDAVAVA AVDGELSYAE LDQRAELLAR RLRASGVGTE
TPVGICLDRT SAMLVAMLGV WRAGGAYVPL DPAFPAGRLR LMLDDAGVRV LVTQGAVRER
MPDLCASVPE LINLDRDEER GCPPDPVTGD PPDPDQLAYV IFTSGSTGRP KGVQVTHGAV
GNLLVAFGES LALTPADRLL AVTTLSFDIS VLELLLPLVH GARVVVAGNA EVVDGAALQA
RLRDSGATVL QGTPATWRML LAAGELPTTV RHRLCGGEAF SRELADRLGG GALWNVYGPT
ETTVWSAAGL VEPAPARPVA IGPPITNTRI HLLDRRGQPV PVGVPGELHI GGAGLARGYL
DRPGLTARKF VPDPFGSPPG GRLYATGDQA RYLPDGRIEF LGRGDQQVKI RGFRVELGEV
EAVLREQTEV GDAAVAAWSD GSDGDARLVA YVVPADGATT DAARLWALLQ PRLALRLPGY
LIPATLVPLD RLPLTPNGKL DRSGLPAPTW GATDATPYVP AGDPVEAAIV RIWEEVLDVR
PVGVETDFFA LGGHSLLAER VLARLRAYFQ LAAPTRVLFE APTVAGLAAA LIRLEPVPGQ
VTAVAEVRAE IETMSPEAVA RLLDGSGQDE VFGSGGVG
//
