ID A0A495KM53_9FLAO Unreviewed; 746 AA.
AC A0A495KM53;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Transporter (CPA2 family) {ECO:0000313|EMBL:RKS02444.1};
GN ORFNames=C8C84_2160 {ECO:0000313|EMBL:RKS02444.1};
OS Flavobacterium sp. 102.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=2135623 {ECO:0000313|EMBL:RKS02444.1, ECO:0000313|Proteomes:UP000270484};
RN [1] {ECO:0000313|EMBL:RKS02444.1, ECO:0000313|Proteomes:UP000270484}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=102 {ECO:0000313|EMBL:RKS02444.1,
RC ECO:0000313|Proteomes:UP000270484};
RA Chistoserdova L.;
RT "Synthetic bacterial communities of pure cultures isolated from sediment of
RT Lake Washington, USA.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000256|ARBA:ARBA00005551}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKS02444.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; RBKX01000001; RKS02444.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495KM53; -.
DR OrthoDB; 9781411at2; -.
DR Proteomes; UP000270484; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR PANTHER; PTHR42751:SF3; NA(+)_H(+) ANTIPORTER; 1.
DR PANTHER; PTHR42751; SODIUM/HYDROGEN EXCHANGER FAMILY/TRKA DOMAIN PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 437..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 530..549
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 578..662
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 663..746
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 746 AA; 83081 MW; 364D727245F87F4E CRC64;
MPMFLSSTTT SVHLPDLISD LGLILITAAI AVLLFRILKQ PLVLGYLVAG FLAGSEFDFF
PTVKDMHSVE VWAEIGVIFL LFSLGLEFSF KKLMKVGGTA SITALTQIIF MITVGFFVGQ
LMGWNKMNSI FLGVILSISS TTIILKTFDE LGVKSQKFAG NVIGSLIVQD IIAILMMVLL
STIAVSQQFS GMELGLAVLK LIFFLTIWFV VGIFFIPTLL KKAKHLLTDE MMLIISLALC
LLMVIFAANV GFSPALGAFI MGSIIAETTQ AEHIEHLVKP VKDLFGAVFF VSVGMLINPE
TLVEYAIPVA ILTFVVIFGQ SISSTIGALL SGQPLKQSIQ TGMSLSQIGE FSFIIATLGT
TLKVTSDFLY PIVVAVSAVT TFTTPFMVKF AVPFSGYLEK KLPRKWVKRI QLYSANTEEI
KSLSNWQIVL RSYLTQVIIH SIIIVAVILL SSNFILPMVQ GSKFGHAIAA LITLVILSPF
LWALSLRRVA VKEVYILMQE RKHHGPIIML VLFRIVLTLF YIGFVLNTFF STGVAFVAFL
IAIGAYILFP KQLHAVYNRI ESHFISNFND RETRKENKRQ NTLSPWDGHM ADFNIAKESN
LAGKTLEELK IREQFGINIA SIRRGDVLIN IPIRSERLFP GDEISIIGTD DQVKEFKIYL
DKNEIDVPEK VEQTDIILQK LELKNRVCIG KTIRESQIRE KTHGIIVGVE RNGKRILNPE
SHLVLEDSDI LWIAGEKKRI AEFMKA
//
