ID A0A495RUK7_SPHMI Unreviewed; 992 AA.
AC A0A495RUK7;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:RKS91227.1};
GN ORFNames=DFR51_0783 {ECO:0000313|EMBL:RKS91227.1};
OS Sphingosinicella microcystinivorans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingosinicellaceae; Sphingosinicella.
OX NCBI_TaxID=335406 {ECO:0000313|EMBL:RKS91227.1, ECO:0000313|Proteomes:UP000276029};
RN [1] {ECO:0000313|EMBL:RKS91227.1, ECO:0000313|Proteomes:UP000276029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19791 {ECO:0000313|EMBL:RKS91227.1,
RC ECO:0000313|Proteomes:UP000276029};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKS91227.1}.
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DR EMBL; RBWX01000007; RKS91227.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495RUK7; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000276029; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 173..432
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 514..596
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 612..877
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 902..984
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 992 AA; 106115 MW; E53BB69D03CFE552 CRC64;
MTSSFRTASG GRVDRDRPVN FTFDGKAYVG LHGDTLASAL LANGVHLVGR SFKYHRPRGI
VGSGADEPNA LVGVRRDAAR YTPNLLATQV ELYDGLAAVS QNRYPSLEYD CMAVNDTLLG
RFIPAGFYYK TFMWPKGAWD KLYEPRIRKA AGLGVAPTAP DPDVYTQRYA HADILVIGAG
PAGIAAAQQA AASGARVILA DDRPAMGGSL LAAADTTVDG EDARAWLRGS LAALAALSNV
TMLPRTIAFG YYPHNWIGLA EKLTDHLPYP ASGQPRERLW QVRARQVVIA AGSIERPLVF
PDNDRPGIML ADAARTYLQE YGVMVGRKAV IVAAHDSAYR VAHELRAAGI EIAAIVDIRS
PVPAAQSARD AGLRVLCDAK VEGTRGRLRV SAITITADGK RETLACDTVL MAGGFTPSVH
LFSQSRGKLV WDEAIQAYLP GESGEAERSA GACRGRFALS EALADGAEAG RSAARDAGFS
PMDLPIPSAQ GARACGGGGH IGAVPTGADL SRAKAFVDWQ NDVTARDIAL AAREGFLSIE
HVKRYTTTGM ATDQGKLSNI NALGIVSNVT GRSIPEIGLT TFRAPYTPVT FGTLAGKARG
DLFDPMRVTA IHDWAAEHGA VFEDVGNWKR ARYFPRHGED MHAAVGRECL QVRNQVGIFD
ASTLGKIEVV GPDAAEFMNR FYVNAWLKLG VGRCRYGVLL REDGFVLDDG VVGRLAPDRF
HVTTTTGGAA RVLAMMEDYL QTEWSDLKVW LTSTTEQWSV IAVQGPKARA VLAPLVTGID
LSAEAFPHMS IADAQICGVP MRLMRVSFTG ELGFEVNVPS GHGRMVWEAI WECGRSNGML
AYGTETMHVL RAEKGFIIIG QETDGTVTPD DAGLGWAIGK AKPDFVGKRS LARPAMIAPD
RKQLVGLLTH DAATVLEEGA QITDPLDPRA AIGHVTSAYH SVALGRSIAL ALVRGGRARM
GHTLHVPMPD GAITAEVVQP VFLDPEGARI HV
//
