ID A0A495SK36_9FLAO Unreviewed; 527 AA.
AC A0A495SK36;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 03-MAY-2023, entry version 12.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=C8C88_2414 {ECO:0000313|EMBL:RKT00583.1};
OS Flavobacterium sp. 123.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=2135627 {ECO:0000313|EMBL:RKT00583.1, ECO:0000313|Proteomes:UP000271452};
RN [1] {ECO:0000313|EMBL:RKT00583.1, ECO:0000313|Proteomes:UP000271452}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=123 {ECO:0000313|EMBL:RKT00583.1,
RC ECO:0000313|Proteomes:UP000271452};
RA Chistoserdova L.;
RT "Synthetic bacterial communities of pure cultures isolated from sediment of
RT Lake Washington, USA.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKT00583.1}.
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DR EMBL; RBXD01000001; RKT00583.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495SK36; -.
DR OrthoDB; 1933776at2; -.
DR Proteomes; UP000271452; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:RKT00583.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000271452};
KW Transferase {ECO:0000313|EMBL:RKT00583.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 308..527
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 527 AA; 60995 MW; CB43E9FE862050D8 CRC64;
MNKLFFRLLV LLMSLSLIGI ILVQVYWFNT SFKNNDEQFK FHVKQVIGNV ADKLQKQEAY
SFYDKYNHLK DSMGKAPKKD DLLEFYYVQK NPRTNKTIVY SNSVISEDYN INGSFFDKRF
DSVKFKSFSS KRVTEVYNNN KIDNSILNQS LIPDIRIEKS GNLDVLDNAQ FEIFYKDITS
AMPLQERVTK ETLRKLIKKE LEEYGVNTKF EFGIYSNGIA TKVKSADFKF DRNATYSIPI
LTDNEGNEKY KLLVTFPHKK KFLLSELVSI TILSIIFTLI IIIAYSSALS QLIRQRQISE
IKNDFINNMT HEFKTPIATI NLALDAIKNP KIIEDKEKVL RYLQMIRDEN KRMHAQVENV
LRISKLEKKE LDIEKESSNV EDIIYDAIDH VNLILEDREG SITTHFDAAR TSVLINDVHF
TNVIVNILEN AIKYSPEVPK IDIYTENIKD MVLVKVKDNG VGMSKAAQKR IFEKFYREHT
GDIHNVKGHG LGLAYVKRIV EDHNGQVYVE SEKGKGSTFI IKIPLIN
//
