ID A0A495VST7_9PSEU Unreviewed; 850 AA.
AC A0A495VST7;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Chitinase (Glycosyl hydrolase family 18) {ECO:0000313|EMBL:RKT51543.1};
GN ORFNames=C8E97_0022 {ECO:0000313|EMBL:RKT51543.1};
OS Saccharothrix australiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=2072 {ECO:0000313|EMBL:RKT51543.1, ECO:0000313|Proteomes:UP000282084};
RN [1] {ECO:0000313|EMBL:RKT51543.1, ECO:0000313|Proteomes:UP000282084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43800 {ECO:0000313|EMBL:RKT51543.1,
RC ECO:0000313|Proteomes:UP000282084};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC class II subfamily. {ECO:0000256|ARBA:ARBA00009121}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKT51543.1}.
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DR EMBL; RBXO01000001; RKT51543.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495VST7; -.
DR OrthoDB; 3882626at2; -.
DR Proteomes; UP000282084; Unassembled WGS sequence.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0030247; F:polysaccharide binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 2.
DR CDD; cd06548; GH18_chitinase; 1.
DR Gene3D; 2.60.40.290; -; 2.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR001919; CBD2.
DR InterPro; IPR008965; CBM2/CBM3_carb-bd_dom_sf.
DR InterPro; IPR012291; CBM2_carb-bd_dom_sf.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR11177; CHITINASE; 1.
DR PANTHER; PTHR11177:SF317; CHITINASE 11; 1.
DR Pfam; PF00553; CBM_2; 2.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00637; CBD_II; 2.
DR SMART; SM00060; FN3; 2.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49384; Carbohydrate-binding domain; 2.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS51173; CBM2; 2.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000282084};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..850
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019861254"
FT DOMAIN 15..125
FT /note="CBM2"
FT /evidence="ECO:0000259|PROSITE:PS51173"
FT DOMAIN 124..233
FT /note="CBM2"
FT /evidence="ECO:0000259|PROSITE:PS51173"
FT DOMAIN 240..326
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 335..420
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 424..850
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT REGION 307..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..337
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 850 AA; 89592 MW; F168391B42363E5F CRC64;
MRRLAIALVA LATIATTVTP ASAAAGLTAT FTRTGTTGKF VVSNPTSAAV TGWSIKFDVP
AGVTVSGAQN ASTTQNGTRV TLTPAYYINT IQPGRNTDPF SPTFTLSREA DPTSCTLNGA
NCDGTGPEPP APAPVTADFS LSGSTGKFIV ANNTDATLSD WAITFTLPSG VTASNANNGT
VSQTGNTVTL APVHYNKSVG PRKTTEPYSP TFTLSRAVEP VTCRINNANC DGSPDVPPTA
PGDLRSPAKT TKSVSLAWNA STAGSLPVAG YDVYNGSTLA TTVTGTSATV TGLTPNTAYS
FTVKAKDTKG TQSPASNALS VTTNNPADDT QPPSAPGNLR GTGKDAGSVT LTWDAATDNS
KVANYDVYQG STVRATVTET TAKIDGLSPS TEYTFSVKAR DIYDNVSGAS NSVKVTTSDI
VGGYAKVGYF VQWGIYGRQF FVKNLDTNGA AAKLTHINYA FGNIDPVNLT CLHGVTKGTS
PNPQDPNQGD GAGDAEADYS RPFSSAQSVD GVADTGWEPL RGNYNQLKKL KAKHPHLKIL
ISLGGWTYSK YFSDVAATDA SRKKFVASCL DIYLKGNLPT YNGAGGPGTA AGIFDGVDLD
WEWPGAEGHP GNHISPNDKR NNTLLIEEFR KQMDELSKTT GKRYQLTAFT PADRAKIDAG
WELAEVAKSM DIFNVQGYDF HGSGSDNSWE PNRTGHQGNL YKDADDPYPF HFSVEDTVNA
YLEAGVNPRK ITVGLAFYGR GWQGVQDGGK KGEWQSATGA APGQFAEEAG TRGYSNLLAS
VPNCTVYHDE AAVATSCFTG NGGQWWTFDD AWAIQKKTAW MKQRGLLGAM IWEMSGDTGV
LMSAVDNGLK
//
