ID A0A495W4Z4_9PSEU Unreviewed; 499 AA.
AC A0A495W4Z4;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=aldehyde dehydrogenase (NAD(+)) {ECO:0000256|ARBA:ARBA00024226};
DE EC=1.2.1.3 {ECO:0000256|ARBA:ARBA00024226};
GN ORFNames=C8E97_5421 {ECO:0000313|EMBL:RKT56712.1};
OS Saccharothrix australiensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=2072 {ECO:0000313|EMBL:RKT56712.1, ECO:0000313|Proteomes:UP000282084};
RN [1] {ECO:0000313|EMBL:RKT56712.1, ECO:0000313|Proteomes:UP000282084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43800 {ECO:0000313|EMBL:RKT56712.1,
RC ECO:0000313|Proteomes:UP000282084};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKT56712.1}.
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DR EMBL; RBXO01000001; RKT56712.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495W4Z4; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000282084; Unassembled WGS sequence.
DR GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR044638; ALDH7A1-like.
DR PANTHER; PTHR43521; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43521:SF1; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000282084}.
FT DOMAIN 4..470
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 234
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 499 AA; 53457 MW; E8F4BFBA437C33F7 CRC64;
MTYVSTNPAD LNDVVARVAL ADAEEFADAA RLAKRAQREW AAVPAPVRGQ VVANLGALVE
SNAEALARIV TREIGKPLAE ARGEVREVAD TCAFFVGEGR RLYGQTVPSE MPDKQLFTFR
DPVGVTAFVT AGNFPIAVPS WYIVPSLLCG NAVVWKPAEY SAACAQAFHD LFVSAGVPDG
VLNVVFAEGS QTYRGLELAL EQRLVDKVGF TGSSEVGALI GELCGRHLQS PCLELGGKNP
MVVTEDADLD LAVRGALFSG FGTGGQRCTS LGTAIVHESV HDEFLRRFTA AVEGAVVGDP
FGDVLYGPML DGKFAVSFEK YLGWIRDHHG VHGSTGVGRI TGANPRKGFL GDPDSGLFYH
PVVVSGVRPD DEVFRHETFG PLVGVTSYRS LDEAVELGNL PGYGLSCSIY TTDPRKVFAF
RRGIGAGMVS VNNSTSGAEA HLPFGGNGRS GNGSRQSGGW VLDQFTRWQS MNWDYSGTLQ
KAQMDTPAIE ADLDFRLEW
//
