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Database: UniProt
Entry: A0A495W585_9PSEU
LinkDB: A0A495W585_9PSEU
Original site: A0A495W585_9PSEU 
ID   A0A495W585_9PSEU        Unreviewed;       187 AA.
AC   A0A495W585;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   13-SEP-2023, entry version 14.
DE   RecName: Full=RNA polymerase sigma factor {ECO:0000256|RuleBase:RU000716};
GN   ORFNames=C8E97_4906 {ECO:0000313|EMBL:RKT56217.1};
OS   Saccharothrix australiensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharothrix.
OX   NCBI_TaxID=2072 {ECO:0000313|EMBL:RKT56217.1, ECO:0000313|Proteomes:UP000282084};
RN   [1] {ECO:0000313|EMBL:RKT56217.1, ECO:0000313|Proteomes:UP000282084}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43800 {ECO:0000313|EMBL:RKT56217.1,
RC   ECO:0000313|Proteomes:UP000282084};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641, ECO:0000256|RuleBase:RU000716}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RKT56217.1}.
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DR   EMBL; RBXO01000001; RKT56217.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A495W585; -.
DR   OrthoDB; 3698333at2; -.
DR   Proteomes; UP000282084; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   CDD; cd06171; Sigma70_r4; 1.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000838; RNA_pol_sigma70_ECF_CS.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR43133:SF52; ECF RNA POLYMERASE SIGMA FACTOR SIGL; 1.
DR   PANTHER; PTHR43133; RNA POLYMERASE ECF-TYPE SIGMA FACTO; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
DR   PROSITE; PS01063; SIGMA70_ECF; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU000716};
KW   Reference proteome {ECO:0000313|Proteomes:UP000282084};
KW   Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW   ECO:0000256|RuleBase:RU000716};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU000716};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU000716}.
FT   DOMAIN          32..100
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          132..181
FT                   /note="RNA polymerase sigma-70 region 4"
FT                   /evidence="ECO:0000259|Pfam:PF04545"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   187 AA;  21446 MW;  4AE5B2909E4CEF6C CRC64;
     MHGVARHRRN TQPRRDQSRP GTSLEDELIR RLYQEFGNAL LGHAMRLTGS DRQWAEDIVQ
     ETLVRAWRNA EKLERDPVLL RSWLFTVARR LVIDDRRKRS ARPRESELTP SDEAPVRDEA
     DRTLAAIVVA EAMNGLTEEH REAILETYLR DRTVGEAAAV LGVPAGTVKS RVYYALRALR
     RALQDRG
//
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