ID A0A495X3W8_9PSEU Unreviewed; 697 AA.
AC A0A495X3W8;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=alpha-galactosidase {ECO:0000256|ARBA:ARBA00012755};
DE EC=3.2.1.22 {ECO:0000256|ARBA:ARBA00012755};
GN ORFNames=DFJ66_1041 {ECO:0000313|EMBL:RKT67864.1};
OS Saccharothrix variisporea.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=543527 {ECO:0000313|EMBL:RKT67864.1, ECO:0000313|Proteomes:UP000272729};
RN [1] {ECO:0000313|EMBL:RKT67864.1, ECO:0000313|Proteomes:UP000272729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43911 {ECO:0000313|EMBL:RKT67864.1,
RC ECO:0000313|Proteomes:UP000272729};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing alpha-D-galactose
CC residues in alpha-D-galactosides, including galactose
CC oligosaccharides, galactomannans and galactolipids.; EC=3.2.1.22;
CC Evidence={ECO:0000256|ARBA:ARBA00001255};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKT67864.1}.
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DR EMBL; RBXR01000001; RKT67864.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495X3W8; -.
DR Proteomes; UP000272729; Unassembled WGS sequence.
DR GO; GO:0004557; F:alpha-galactosidase activity; IEA:InterPro.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd14791; GH36; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 2.70.98.60; alpha-galactosidase from lactobacil brevis; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR038417; Alpga-gal_N_sf.
DR InterPro; IPR002252; Glyco_hydro_36.
DR InterPro; IPR031704; Glyco_hydro_36_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43053:SF3; ALPHA-GALACTOSIDASE C-RELATED; 1.
DR PANTHER; PTHR43053; GLYCOSIDASE FAMILY 31; 1.
DR Pfam; PF16875; Glyco_hydro_36N; 1.
DR Pfam; PF02065; Melibiase; 1.
DR PRINTS; PR00743; GLHYDRLASE36.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000272729}.
FT DOMAIN 80..171
FT /note="Glycosyl hydrolase family 36 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16875"
SQ SEQUENCE 697 AA; 76250 MW; 7AA8FCEA8A1FB3B9 CRC64;
MTRFQWGNDV LAAEFALTED GVLRLERLGA PGESHPEYHE AAPAPITAVT ATGHGRNWSG
NRWIHSAIGE RLRHKDHYST HKDGLSTLTV RLHDPETGLV AEVVYRLADG VPVLRAEVLL
RNEGRIPLHL EAVASLAVGC LTEALEDADL LWADNDWLAE CRWQRRPLRE TSPALDGRVR
TGNGRGAFVL AGQGAWASGG KLPMGGLTDR RSGRTWLWQV EHNGGGWRWE CGEREHAAYL
ALFGPSESLH AWRHTLEPGA EFRTVPVALA FSADGPDGAF AALTEHRRAT RRPHPDHERL
PVIFNDYMNC LMGDPTTAKL LPLVDAAAEA GAEYFVIDAG WYADEAENWW NTVGAWEPSR
TRFPGARGIH EVLDHIRDLG MVPGLWLEPE VVGTGSAVAN ALPDEAFFRR NGVRVVEAGR
YHLDLRHPAA RAHLDRVVDR LVAEWGVGYL KLDHNVDPGP GTSAHPGESP GAGLLGHHRA
HLDWLDGVLD RYPRLVVENC ASGGMRMDHA LLSRLQVQST SDQENLVHYA PIAAAAPTAV
TPEQGAVWAY PRGEDTLDEV AFTMASALLG RVHLSGRITE LDPEARALVH EAVAVYKAIR
ADLPVALPSW PLGLPAWDDP WVALALRTPS TTYVTAWRRG GEPTTTLQLP HLVGVDARVN
VLYPSTSPAA VEWHADRAAL SLTLPAAPSA VLVRLER
//
