ID A0A495XC52_9PSEU Unreviewed; 398 AA.
AC A0A495XC52;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=DFJ66_4500 {ECO:0000313|EMBL:RKT71219.1};
OS Saccharothrix variisporea.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=543527 {ECO:0000313|EMBL:RKT71219.1, ECO:0000313|Proteomes:UP000272729};
RN [1] {ECO:0000313|EMBL:RKT71219.1, ECO:0000313|Proteomes:UP000272729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43911 {ECO:0000313|EMBL:RKT71219.1,
RC ECO:0000313|Proteomes:UP000272729};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKT71219.1}.
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DR EMBL; RBXR01000001; RKT71219.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495XC52; -.
DR OrthoDB; 9809531at2; -.
DR Proteomes; UP000272729; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR PANTHER; PTHR11669:SF70; POSSIBLE DNA POLYMERASE; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 4: Predicted;
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000272729};
KW Transferase {ECO:0000256|ARBA:ARBA00022932}.
FT REGION 278..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 398 AA; 41784 MW; 1E10502F04B2EB32 CRC64;
MKGVWSEVVG QPDAVAVLSA AAEAAATIVA GGTPAPGAMT HAWLFTGPPG SGRSGAARAF
AAALQCTTVD DRPGCGECSG CHTTLAGTHA DVRVVAPEGL SISVAEMRSL VQVSARRPTS
GRWQVVIITD ADRLTEGAAN ALLKAVEEPP DRTVFLLCAP SDHPDDVSVT IRSRCRIVRL
GTPRPDAIAE ALRAEGVPAP DAEWAASVSG GHVGRARRLA TDEAVRARRD AVLRIPLALR
RPADIFTCAD SLVQAAEADA LTANEARDEA ERQALETAMG AGGTGKGTAA ATRGAKGALK
DLEKRQKSRA TRTQRDSLDQ ALVDLAAFYR DVLVTATGAQ AVLNHPDRAD DAREAARTWS
RESTLRRLEA VLACREALEL NVKPRIAVEA MLTTLHRG
//
