ID A0A495XHF3_9PSEU Unreviewed; 700 AA.
AC A0A495XHF3;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=alpha-galactosidase {ECO:0000256|ARBA:ARBA00012755};
DE EC=3.2.1.22 {ECO:0000256|ARBA:ARBA00012755};
GN ORFNames=DFJ66_5923 {ECO:0000313|EMBL:RKT72606.1};
OS Saccharothrix variisporea.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=543527 {ECO:0000313|EMBL:RKT72606.1, ECO:0000313|Proteomes:UP000272729};
RN [1] {ECO:0000313|EMBL:RKT72606.1, ECO:0000313|Proteomes:UP000272729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43911 {ECO:0000313|EMBL:RKT72606.1,
RC ECO:0000313|Proteomes:UP000272729};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing alpha-D-galactose
CC residues in alpha-D-galactosides, including galactose
CC oligosaccharides, galactomannans and galactolipids.; EC=3.2.1.22;
CC Evidence={ECO:0000256|ARBA:ARBA00001255};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKT72606.1}.
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DR EMBL; RBXR01000001; RKT72606.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495XHF3; -.
DR Proteomes; UP000272729; Unassembled WGS sequence.
DR GO; GO:0004557; F:alpha-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd14791; GH36; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 2.70.98.60; alpha-galactosidase from lactobacil brevis; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR038417; Alpga-gal_N_sf.
DR InterPro; IPR002252; Glyco_hydro_36.
DR InterPro; IPR031705; Glyco_hydro_36_C.
DR InterPro; IPR031704; Glyco_hydro_36_N.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43053:SF3; ALPHA-GALACTOSIDASE C-RELATED; 1.
DR PANTHER; PTHR43053; GLYCOSIDASE FAMILY 31; 1.
DR Pfam; PF16874; Glyco_hydro_36C; 1.
DR Pfam; PF16875; Glyco_hydro_36N; 1.
DR Pfam; PF02065; Melibiase; 1.
DR PRINTS; PR00743; GLHYDRLASE36.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000272729}.
FT DOMAIN 23..244
FT /note="Glycosyl hydrolase family 36 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16875"
FT DOMAIN 603..685
FT /note="Glycosyl hydrolase family 36 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16874"
SQ SEQUENCE 700 AA; 76904 MW; B9DCD7C42560692B CRC64;
MADVTHLRAA GVSLVLDHRG GTLPRVLHWG ADLGPVDLDS LALATAPQPV GYSADGPVEV
AVLPEQSAGW LGTPGLVGNR AGRAFSTAFR VVEVDGTTYR AVDEAAGLEL RLEVELTDSG
LVRQRASVTN TGDSDFAVDA LSVTLPVPAE AVEILDFTGR WTRERSPQRT RFTQGLRVRE
NRTGRTGFDS AYLMAAGTEG FGNRSGEIWA VHTAWSGNHR TFAERTRHAV SLLGSGELLL
SGEVVLAPGE TYRSPWQFGS YGVGLDAVSA RFHEWMRARP NHPRSPRPVV VNTWEAVYFD
HDLTRLKALA DKAAEVGAER FVLDDGWFGS RRDDSSGLGD WYVSDEVWPD GLGPLIDHVT
ARGMQFGLWV EPEMVNENSD LARAHPDWIM SPGDRLPRKA RHQQVLDLAN PEAFKYVLER
LDDLLTTYDI AYLKWDHNRD LVEAGHQGKP GVHGQTVALY RLLDELRTRH PSVEIESCSS
GGGRVDLEVL QRTDRVWASD CIDALERQSI QRWTNVLVPL ELIGSHIGAD TSHTTHRRHP
VDFRAGTALF GHFGIEWDLM AAGPEELERL TAWVALYKEL RGLLHTGTSV HGDHPDPAVS
VHGVVAADRT DAVFAVVSTA TSEVYPTGAV RLPGLDPDRS YHVRPLPPGD VPDGNPHHWG
VKLPWWEKGV ELTGRALTST GVQSPVLYPE RLILLRATAI
//
