ID A0A495XID4_9PSEU Unreviewed; 581 AA.
AC A0A495XID4;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:RKT74251.1};
GN ORFNames=DFJ66_7594 {ECO:0000313|EMBL:RKT74251.1};
OS Saccharothrix variisporea.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=543527 {ECO:0000313|EMBL:RKT74251.1, ECO:0000313|Proteomes:UP000272729};
RN [1] {ECO:0000313|EMBL:RKT74251.1, ECO:0000313|Proteomes:UP000272729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43911 {ECO:0000313|EMBL:RKT74251.1,
RC ECO:0000313|Proteomes:UP000272729};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKT74251.1}.
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DR EMBL; RBXR01000001; RKT74251.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495XID4; -.
DR OrthoDB; 9813184at2; -.
DR Proteomes; UP000272729; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000272729}.
FT DOMAIN 11..323
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 367..475
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 494..552
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 152
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 228
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 581 AA; 64180 MW; C19A8774579700F5 CRC64;
MTTFAIQDNG FVRNGRPHRV LSGALHYFRS HPAQWPRRLS VLRGMGLNTV ETYVPWNLHE
PTPGRYHDLD ALTRFLDAAA AEGLDAIVRP GPYICAEWEN GGLPWWLSGP LRCAHPDFLA
AVDSWFDVLV PRIAARQTTR GGNVVMVQVE NEYGSYGSDH TYLRHLRDGL MERGIDVPLF
TSDGGEALFL TGGLVPDTLG TVNFGSDAAG QFAEFRRHRP RDPLFCMEFW DGWFDHWGDR
HTTRSPEDAA AALDEVLAAG ASVNLYMAHG GTNFGFWAGA NAGGDVHDGA YRPTVTSYDY
DAPMDEAGNP TPKYWVFREV IGKYAPLPAP PPPPPATLPA ATVPLTRSVR LTDVFRTPTT
HTPHVPSFEE LNQHQGFLLH RTTLPGPRPP LPLRLRDLRD RAQLFVDGTE HAVFSRAADP
TAVDHTDVPG GVTVELLVEA MGRINYGPLL GERKGILGGV LHERQYVHGW ETTPIPLDTL
PELPWDTGTS THGPLFLGGT LTVTDPRDAY LDLTGWTKGV VWVNGFCLGR YWHIGPQRTL
YVPEPVLHQG DNDITILELH PDASPRSVQV SPHPVLEGDP R
//
