ID A0A495Y3L2_9MICO Unreviewed; 331 AA.
AC A0A495Y3L2;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 13-SEP-2023, entry version 12.
DE SubName: Full=Chloramphenicol-sensitive protein RarD {ECO:0000313|EMBL:RKT78858.1};
GN ORFNames=DFJ68_2312 {ECO:0000313|EMBL:RKT78858.1};
OS Terracoccus luteus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Terracoccus.
OX NCBI_TaxID=53356 {ECO:0000313|EMBL:RKT78858.1, ECO:0000313|Proteomes:UP000278440};
RN [1] {ECO:0000313|EMBL:RKT78858.1, ECO:0000313|Proteomes:UP000278440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44267 {ECO:0000313|EMBL:RKT78858.1,
RC ECO:0000313|Proteomes:UP000278440};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the EamA transporter family.
CC {ECO:0000256|ARBA:ARBA00007362}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKT78858.1}.
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DR EMBL; RBXT01000001; RKT78858.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A495Y3L2; -.
DR OrthoDB; 369870at2; -.
DR Proteomes; UP000278440; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR004626; RarD.
DR NCBIfam; TIGR00688; rarD; 1.
DR PANTHER; PTHR22911; ACYL-MALONYL CONDENSING ENZYME-RELATED; 1.
DR PANTHER; PTHR22911:SF137; PROTEIN RARD; 1.
DR Pfam; PF00892; EamA; 2.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000278440};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 31..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..165
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT DOMAIN 175..308
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 331 AA; 34549 MW; 07F837B53CC94736 CRC64;
MTSGAASPGP RPTAAPTGIL DTSPTGEVTR GTVLGFAAYG LWGLFPLYFD ALRPAGAWEI
LAHRILWTLL FCVVVLAVMR DVSWVRPLLH RPKLLAGIAV AAVLIAVNWT VYVAAVTSGN
TSDAALGYFL NPLVTVALGV VVLGERLRVL QWVAVGVGVS AAVFLAVAGG QVPVVALTLA
FSFALYGLTK KKIGASLEAV HGLTVETVVL APVAVVTLLV VHAQGGLEFG RHGALHTGLL
VFSGVATALP LLCFAAAARR IPLVTIGLIQ FITPVMQLLC AVLLLGEHMP AERWVGFGIV
WVALVVLTVD SLVAVGRSRR AAALPVDDCP R
//
