ID   A0A498BY95_9MICO        Unreviewed;       371 AA.
AC   A0A498BY95;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE            EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
GN   ORFNames=C7474_2394 {ECO:0000313|EMBL:RLK47797.1};
OS   Microbacterium telephonicum.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Microbacterium.
OX   NCBI_TaxID=1714841 {ECO:0000313|EMBL:RLK47797.1, ECO:0000313|Proteomes:UP000273158};
RN   [1] {ECO:0000313|EMBL:RLK47797.1, ECO:0000313|Proteomes:UP000273158}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S2T63 {ECO:0000313|EMBL:RLK47797.1,
RC   ECO:0000313|Proteomes:UP000273158};
RX   PubMed=26203337; DOI=.1186/s40793-015-0017-x;
RA   Whitman W.B., Woyke T., Klenk H.P., Zhou Y., Lilburn T.G., Beck B.J.,
RA   De Vos P., Vandamme P., Eisen J.A., Garrity G., Hugenholtz P.,
RA   Kyrpides N.C.;
RT   "Genomic Encyclopedia of Bacterial and Archaeal Type Strains, Phase III:
RT   the genomes of soil and plant-associated and newly described type
RT   strains.";
RL   Stand. Genomic Sci. 10:26-26(2015).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RLK47797.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; RCDB01000003; RLK47797.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498BY95; -.
DR   OrthoDB; 9779574at2; -.
DR   Proteomes; UP000273158; Unassembled WGS sequence.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000273158}.
FT   DOMAIN          20..365
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   371 AA;  40063 MW;  B4B19717FDE7F5B2 CRC64;
     MAIDPHADPK LQGVSIRSLP KVSLHDHLDG ALRPATVIEL ADAIGLDVPE QNAAELGDWF
     AEKSDSGSLV EYLKTFDVTT SVMQTADGLR RVAKEFVEDL AADGVIYGEV RWAPEQHLAR
     GLSLEDAVEA VQDGIEEGED AAEAAGHDIR VGQLITAMRH ADRSLEIAKL AVAFRGRGAV
     GFDIAGAEDG FPASNHRAAF DYLASEFFPV TVHAGEAAGL DSIRSALIDG RALRLGHGVR
     IAEDLEVVSQ KGEETFVTFG DLARWVRDRE IPLELSPSSN LQTGAIAAWG SELADHPFDL
     LYQLGFSVTV NVDNRLMSRT SLTRELALLA DAFEYGLDDL EAFQLNAAAA AFLSVEEREE
     LIELIGDGFT R
//