ID   A0A498CWU6_9FIRM        Unreviewed;       715 AA.
AC   A0A498CWU6;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Antibiotic ABC transporter permease {ECO:0000313|EMBL:RLL08978.1};
GN   ORFNames=D4A47_11255 {ECO:0000313|EMBL:RLL08978.1};
OS   Anaerotruncus massiliensis (ex Liu et al. 2021).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Anaerotruncus.
OX   NCBI_TaxID=2321404 {ECO:0000313|EMBL:RLL08978.1, ECO:0000313|Proteomes:UP000276301};
RN   [1] {ECO:0000313|EMBL:RLL08978.1, ECO:0000313|Proteomes:UP000276301}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=22A2-44 {ECO:0000313|EMBL:RLL08978.1,
RC   ECO:0000313|Proteomes:UP000276301};
RA   Wang Y.-J.;
RT   "Anaerotruncus faecis sp. nov., isolated from human feces.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RLL08978.1}.
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DR   EMBL; RCHT01000026; RLL08978.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498CWU6; -.
DR   Proteomes; UP000276301; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000276301};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        178..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        204..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        312..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        359..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        528..555
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        567..588
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        625..642
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        654..676
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          81..330
FT                   /note="Membrane transport protein MMPL"
FT                   /evidence="ECO:0000259|Pfam:PF03176"
FT   DOMAIN          463..676
FT                   /note="Membrane transport protein MMPL"
FT                   /evidence="ECO:0000259|Pfam:PF03176"
SQ   SEQUENCE   715 AA;  78806 MW;  A1100866740CBDC7 CRC64;
     MLKKFARALT RSPKTIILLA LLLLLPSLYG AINTRVNYDI LSYLPEELDS SQGQAVLEDT
     FHSAATAMLV VEGMPARDVE KLRDAIEEVP GVSDAMWISS MLDISVPKEI LPDEIKDIFY
     SEKAKDSTMI IVQFEHPGAS NETLRAIDEV RALCDERCFL AGVSIFLKDT KDLVEQEMPF
     YTLLAVVFSI VAMSLTMESV VLPFVFLMGI GFAVAYNFGS NIFLGQVSYI TKAIAAILQL
     GVSMDYSIFL FDRYDEEKER FEDRRDAMAS AIQGAFVSLS GSSTTTVAGF LALCAMRLGL
     GPDLGLVMAK GIVIGILVVL VVLPSLILVF DKPIHRWSHR SLIPDLTRLN DWIIDHKKTF
     VAIFLVLFVP ALIMQSRTQI YYNIDQSLPE DLPSTVATNK LKDEFDMATT HFVIVDDSLP
     AYRLNAMEKE MEKVDGVEAL LAYNKFVGPG IPDNFIPQEL KDICKKDGKQ MLMINSRYKA
     AREEENAQIE ALNEIAKRYD PGALITGEGA MTKDLMDITT VDIQVTNVLS VLAILVIVGL
     TFKSFTVPVI LVAAIELSIF INQGIPALTG TVIPFVSPIV IGCIQLGATV DYAILMTTRF
     REELQNGHER VEAIKIASSA SDKSIITSAS VFFCATFGVS LISKIEIIKS ICSMLARGAV
     ISALVSIFIL PSVLLACEGF IAKTSHNWRS DITPPPRKRL GKRLKELHAK QGESI
//