ID A0A498DG09_9BACI Unreviewed; 382 AA.
AC A0A498DG09;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Thiolase family protein {ECO:0000313|EMBL:RLL46881.1};
GN ORFNames=D8M04_06695 {ECO:0000313|EMBL:RLL46881.1};
OS Oceanobacillus piezotolerans.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX NCBI_TaxID=2448030 {ECO:0000313|EMBL:RLL46881.1, ECO:0000313|Proteomes:UP000270219};
RN [1] {ECO:0000313|EMBL:RLL46881.1, ECO:0000313|Proteomes:UP000270219}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YLB-02 {ECO:0000313|EMBL:RLL46881.1,
RC ECO:0000313|Proteomes:UP000270219};
RA Yu L.;
RT "Oceanobacillus sp. YLB-02 draft genome.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLL46881.1}.
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DR EMBL; RCHR01000002; RLL46881.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498DG09; -.
DR OrthoDB; 2774224at2; -.
DR Proteomes; UP000270219; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000270219};
KW Transferase {ECO:0000256|RuleBase:RU003557}.
FT DOMAIN 7..251
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 258..380
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 91
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 337
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 367
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 382 AA; 41032 MW; CA5D4898DE2587DE CRC64;
MGNRDAVIVE AVRLPVGRRK GVYSDTRAEY LLAAILKGVM DRTGIDAGLI DDIIVGCVTQ
NEEQGNNIAR IASLMAGLPK DVPAMTINRK CGSSQHAVNQ AAQSIISGDC DVVIAAGVEH
MTRHPMGSDK VPEPEELNEK YEVVTQGEAA ERIADKWGFS REELDDFAVR SHKLAAKASE
NGAFHREILP IEVEKDGERI LVTEDEGIRP NSSVKKLAAL KTVFREEGKI TAGNASQISD
GAAAVLIMSR EKAEALGLKP RAKIVARDVI GSDPTLMLTG PIPLTKRLLE KTGLCVSDID
VFECNEAFAS VALAWMMEIQ PDIEKVNPRG GAIALGHPTG ASGARIMTTL LHELEDLDKR
YGLQVMCCGG GMATGTVIER VN
//
