ID A0A498E9C2_9ACTN Unreviewed; 653 AA.
AC A0A498E9C2;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=cellulose synthase (UDP-forming) {ECO:0000256|ARBA:ARBA00012539};
DE EC=2.4.1.12 {ECO:0000256|ARBA:ARBA00012539};
GN ORFNames=D7M15_09490 {ECO:0000313|EMBL:RLL70317.1};
OS Streptomyces sp. Z26.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2500177 {ECO:0000313|EMBL:RLL70317.1, ECO:0000313|Proteomes:UP000288048};
RN [1] {ECO:0000313|EMBL:RLL70317.1, ECO:0000313|Proteomes:UP000288048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z26 {ECO:0000313|EMBL:RLL70317.1,
RC ECO:0000313|Proteomes:UP000288048};
RA Buchmann A., Cano-Prieto C., Baz M., Hassani L., Barakate M., Nafis A.,
RA Niedermeyer T.H.J., Gross H.;
RT "Draft Genome Sequence of the Novonestmycin-Producing Strain Streptomyces
RT sp. Z26, isolated from potato rhizosphere in Morocco.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLL70317.1}.
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DR EMBL; RCHV01000002; RLL70317.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498E9C2; -.
DR OrthoDB; 9806824at2; -.
DR Proteomes; UP000288048; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd06421; CESA_CelA_like; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF2; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Cellulose biosynthesis {ECO:0000256|ARBA:ARBA00022916};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000288048};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:RLL70317.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 74..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 458..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 542..561
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 256..446
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF13632"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 591..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 591..606
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..632
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 653 AA; 72859 MW; 86BF0D489DB1556B CRC64;
MRLPRHRRPD PAGDDPGTAP HATPGRATRW PRKELPRYDY EHYSRLAGPL SQPDRDQPYR
VRYRSLLADE PHRVRAAFLL CLAPLLSAGL LLWLMQPQHW TERDNGEVSD LVLKLDIVML
VSIGLIELFR TLNVISNAHA TLVARDPVPV VPEPGTRVAF LTSFVPGKEP LEMVTRTLEA
AVRVRHRGTV HVWLLDEGDD PEVREVCRRL GVRHFSRKGV ARWNQEKGPH RAKTKHGNYN
AWLDAHGDDY DYFASVDTDH VPLPNYLERM LGYFRDPDVG FVIGPQVYGN YDNFVTKAAE
SQQFLFHALI QRAGNRYEAP MFVGTSNAVR ISALKGIGGL YDSITEDMAT GFEMHRSRNP
GTGNRWRSVY TPDVLAVGEG PNAWTDFFTQ QLRWSRGTYE TILTQYWRGL FTLGPGKLFN
YTMLMIFYPI SALNWILAAL SCALFLGVGA SGVQIDPTIW MMLYGNASAL QIGLYVWNRR
HNVSPHEPEG SGGLAGMLMS ALSAPIYARS LFDTVLRRKS GFVVTPKGDS ASPDTFFGTF
RVHLFFIAVF GGSFVGSVFL GHDHPAMLTW AALAMLITAA PIIGWRVTLH AERKKRKHGR
TRRRSGRRGA QGQDGQGPPP GGPPPPGTDP AARPDPSATH DETMQTALGG RDQ
//
