ID   A0A498GA27_9EURY        Unreviewed;       432 AA.
AC   A0A498GA27;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Malate synthase {ECO:0000313|EMBL:RLM90361.1};
GN   ORFNames=D3D02_06280 {ECO:0000313|EMBL:RLM90361.1};
OS   Halobellus sp. Atlit-38R.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Halobellus.
OX   NCBI_TaxID=2282131 {ECO:0000313|EMBL:RLM90361.1, ECO:0000313|Proteomes:UP000277703};
RN   [1] {ECO:0000313|EMBL:RLM90361.1, ECO:0000313|Proteomes:UP000277703}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Atlit-38R {ECO:0000313|EMBL:RLM90361.1,
RC   ECO:0000313|Proteomes:UP000277703};
RA   Turgeman-Grott I.;
RT   "Pervasive acquisition of CRISPR memory from multiple replicons driven by
RT   inter-species mating of archaea.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RLM90361.1}.
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DR   EMBL; QXIJ01000003; RLM90361.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498GA27; -.
DR   Proteomes; UP000277703; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 1.20.58.1560; -; 1.
DR   Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR   InterPro; IPR005000; Aldolase/citrate-lyase_domain.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR   NCBIfam; NF041315; malate_syn_AceB_Halo; 1.
DR   PANTHER; PTHR32308:SF10; CITRATE LYASE SUBUNIT BETA; 1.
DR   PANTHER; PTHR32308; LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED; 1.
DR   Pfam; PF03328; HpcH_HpaI; 1.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE   4: Predicted;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277703}.
FT   DOMAIN          39..254
FT                   /note="HpcH/HpaI aldolase/citrate lyase"
FT                   /evidence="ECO:0000259|Pfam:PF03328"
SQ   SEQUENCE   432 AA;  47710 MW;  8E628418AE6BE699 CRC64;
     MERRHDRQFV RTFFTSPTAV EGEDNSAKML EGAATLRGLQ APDVWVPDNE DATAPSMRDE
     GAENIVEVVS EHGADFPGEI HPRVVWHRDS PATRYQGLQQ MLTITDPEGG AAAHIDGFVI
     PEVGDIDDWK KADEAITWVE TENGLDEGSL TMSVIVESGA AELAMGDLRE EMGKPSNNLE
     RLFLLVDGEV DYTKDMRAMT PTGELPAWPE LRHNTSRGAS AAGCIAVDGP YDDIRDVEGY
     HERMTENRAK GMTGIWSLTP GQVQEANTAP LPPKTGSWLL DLGSREVELE DAGDAQVYDG
     DRLSLIETSD GYHLTVGSEE LELDEDELRE ELLDRTAYIP SLDDVVDSME EFEAAKEAGK
     GAIAMTRAAT LRLDGVEIDI EADRMWDEAT YQAAMTPIAL FQDVYEHRPD QHEELIERYS
     EDVVDRATAV GN
//