ID   A0A498GZR3_9EURY        Unreviewed;       293 AA.
AC   A0A498GZR3;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=2-ketoisovalerate ferredoxin oxidoreductase {ECO:0000313|EMBL:RXE55617.1};
DE            EC=1.2.7.7 {ECO:0000313|EMBL:RXE55617.1};
GN   ORFNames=ABH15_05005 {ECO:0000313|EMBL:RXE55617.1};
OS   Methanoculleus taiwanensis.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
OX   NCBI_TaxID=1550565 {ECO:0000313|EMBL:RXE55617.1, ECO:0000313|Proteomes:UP000290932};
RN   [1] {ECO:0000313|EMBL:RXE55617.1, ECO:0000313|Proteomes:UP000290932}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CYW4 {ECO:0000313|EMBL:RXE55617.1,
RC   ECO:0000313|Proteomes:UP000290932};
RX   PubMed=25575827; DOI=.1099/ijs.0.000062;
RA   Weng C.Y., Chen S.C., Lai M.C., Wu S.Y., Lin S., Yang T.F., Chen P.C.;
RT   "Methanoculleus taiwanensis sp. nov., a methanogen isolated from deep
RT   marine sediment at the deformation front area near Taiwan.";
RL   Int. J. Syst. Evol. Microbiol. 65:1044-1049(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RXE55617.1}.
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DR   EMBL; LHQS01000002; RXE55617.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498GZR3; -.
DR   OrthoDB; 296931at2157; -.
DR   Proteomes; UP000290932; Unassembled WGS sequence.
DR   GO; GO:0043807; F:3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity; IEA:UniProtKB-EC.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR   GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR   GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR   CDD; cd03376; TPP_PFOR_porB_like; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR   PANTHER; PTHR42897:SF1; 2-OXOACID OXIDOREDUCTASE (FERREDOXIN); 1.
DR   PANTHER; PTHR42897; PYRUVATE SYNTHASE SUBUNIT PORB; 1.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000313|EMBL:RXE55617.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000290932}.
FT   DOMAIN          56..199
FT                   /note="Thiamine pyrophosphate enzyme TPP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02775"
FT   REGION          133..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        133..151
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   293 AA;  31500 MW;  070AFF4FFAA40DF5 CRC64;
     MTAIPKEEYL LKCTSACAGC SSSLCLRYVT KAAGPDTVLV VPACCTSVIQ GIYPNTAMDI
     PVYNIAFAAA AACASGMSNA FRALERDTNV IVYAGDGGTV DIGIQALSGA FERGTDFLYI
     CYDNEAYGNT GMQRSGATPL GARTTTTPGG KPTPKKDLDR IVEAHNPPYM ATACSAYPLD
     LYKKVKKALS IEGPKFIHIL APCPPGWRYS SEKTVEMGKL AVKTGSWVLY ERENGALTIN
     GPSKAAMKKP LPLEDYIRGQ GRFKGITPEA LEEMRRQIQM TNARLSREAE GIC
//