ID A0A498HPW0_MALDO Unreviewed; 402 AA.
AC A0A498HPW0;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE RecName: Full=GPN-loop GTPase 2 {ECO:0000256|RuleBase:RU365059};
GN ORFNames=DVH24_012563 {ECO:0000313|EMBL:RXH72879.1};
OS Malus domestica (Apple) (Pyrus malus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX NCBI_TaxID=3750 {ECO:0000313|EMBL:RXH72879.1, ECO:0000313|Proteomes:UP000290289};
RN [1] {ECO:0000313|EMBL:RXH72879.1, ECO:0000313|Proteomes:UP000290289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. HFTH1 {ECO:0000313|Proteomes:UP000290289};
RC TISSUE=Young leaf {ECO:0000313|EMBL:RXH72879.1};
RA Hu J.;
RT "A high-quality apple genome assembly.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Small GTPase required for proper localization of RNA
CC polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly
CC step prior to nuclear import. {ECO:0000256|RuleBase:RU365059}.
CC -!- SUBUNIT: Binds to RNA polymerase II (RNAPII).
CC {ECO:0000256|RuleBase:RU365059}.
CC -!- SIMILARITY: Belongs to the GPN-loop GTPase family.
CC {ECO:0000256|ARBA:ARBA00005290, ECO:0000256|RuleBase:RU365059}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXH72879.1}.
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DR EMBL; RDQH01000341; RXH72879.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498HPW0; -.
DR STRING; 3750.A0A498HPW0; -.
DR Proteomes; UP000290289; Chromosome 15.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17871; GPN2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004130; Gpn.
DR InterPro; IPR030231; Gpn2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR21231:SF3; GPN-LOOP GTPASE 2; 1.
DR PANTHER; PTHR21231; XPA-BINDING PROTEIN 1-RELATED; 1.
DR Pfam; PF03029; ATP_bind_1; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|RuleBase:RU365059};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU365059};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU365059};
KW Reference proteome {ECO:0000313|Proteomes:UP000290289}.
FT REGION 374..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 402 AA; 45849 MW; 3834D5CD3A5E3217 CRC64;
MVFGQVVIGP PGSGKTTYCN GMSQFLQLIG RKVAVVNLDP ANDALPYPFQ FFRVLLFNVE
PLREYRYECA VNIEDLVKLS DVMVEHSLGP NGGLVYCMDY LEKNFDWLEA KLKPLMKDHY
ILFDLPGQVE LFFLHSNAKN VIMKLVKKLN LRLTAVHLVD AHLCSDPGKY VSALILSLST
MLHMELPHIN VLSKIDLIES YGKLAFNLDF FTDVEDLSYL QYKLDQDPRS AKYRKLTKEL
CESCQFCNLR YPGMPVPIRF TPDLLNFLCL VFSHATFQDK ESVGNLVKLI DKSNGYIFAG
IDASAVEFSK IAVGPVDWDY YRYPFYFDST IKSLRVAPYL VKILSHQYLH YQETTFSVSL
NKVAHSCSSA REKSMTVPSL TSDRKNSQPH GYFMPKRSGN SR
//
