ID A0A498HPY3_MALDO Unreviewed; 388 AA.
AC A0A498HPY3;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=3,5-dihydroxybiphenyl synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=DVH24_012048 {ECO:0000313|EMBL:RXH72364.1};
OS Malus domestica (Apple) (Pyrus malus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX NCBI_TaxID=3750 {ECO:0000313|EMBL:RXH72364.1, ECO:0000313|Proteomes:UP000290289};
RN [1] {ECO:0000313|EMBL:RXH72364.1, ECO:0000313|Proteomes:UP000290289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. HFTH1 {ECO:0000313|Proteomes:UP000290289};
RC TISSUE=Young leaf {ECO:0000313|EMBL:RXH72364.1};
RA Hu J.;
RT "A high-quality apple genome assembly.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXH72364.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; RDQH01000341; RXH72364.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498HPY3; -.
DR EnsemblPlants; mRNA:MD15G0115300; mRNA:MD15G0115300; MD15G0115300.
DR Gramene; mRNA:MD15G0115300; mRNA:MD15G0115300; MD15G0115300.
DR Proteomes; UP000290289; Chromosome 15.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0019748; P:secondary metabolic process; IEA:UniProt.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF108; CHALCONE SYNTHASE-LIKE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW Reference proteome {ECO:0000313|Proteomes:UP000290289};
KW Transferase {ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 11..223
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 233..383
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 159
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 388 AA; 42994 MW; 96B5A51378423595 CRC64;
MAPLVKNEPQ HAKILAIGTA NPPNVYHQKD YPDFLFRVTK NEHRTDLREK FDRICEKSRT
KKRYLHLTEE MLKANPNIYT YGAPSLDVRQ DICNIEVPKL GQEAALKAIK EWGQPISKIT
HLIFCTASCV DMPGCDFQLI KLLGLDPSVT RTMIYEAGCY AGATVLRMAK DFAENNKGAR
VLVVCAEITT VFFHGLTDTH LDILVGQALF ADGASAVIVG ANPEPEIERP LFEIVACRQT
ILPNSEHGVV ANIREMGFNY YLSGDVPKFV GGNVVDFMTK TFEKVDGKKK DWNSLFFSVH
PGGPAIVDQV EEKLGLKEGK LRATRHVLSE YGNMGAPTVH FILDEMRNKS IEEGKTTTGE
GLEWGVVIGI GPGLTVETAV LRSESIRC
//
