ID   A0A498HTZ4_MALDO        Unreviewed;       865 AA.
AC   A0A498HTZ4;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Chalcone synthase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DVH24_012047 {ECO:0000313|EMBL:RXH72363.1};
OS   Malus domestica (Apple) (Pyrus malus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX   NCBI_TaxID=3750 {ECO:0000313|EMBL:RXH72363.1, ECO:0000313|Proteomes:UP000290289};
RN   [1] {ECO:0000313|EMBL:RXH72363.1, ECO:0000313|Proteomes:UP000290289}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. HFTH1 {ECO:0000313|Proteomes:UP000290289};
RC   TISSUE=Young leaf {ECO:0000313|EMBL:RXH72363.1};
RA   Hu J.;
RT   "A high-quality apple genome assembly.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC       ECO:0000256|RuleBase:RU003633}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RXH72363.1}.
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DR   EMBL; RDQH01000341; RXH72363.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498HTZ4; -.
DR   STRING; 3750.A0A498HTZ4; -.
DR   Proteomes; UP000290289; Chromosome 15.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0019748; P:secondary metabolic process; IEA:UniProt.
DR   CDD; cd00831; CHS_like; 2.
DR   Gene3D; 3.40.47.10; -; 4.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877:SF108; CHALCONE SYNTHASE-LIKE; 1.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 2.
DR   Pfam; PF00195; Chal_sti_synt_N; 2.
DR   SUPFAM; SSF53901; Thiolase-like; 4.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW   Reference proteome {ECO:0000313|Proteomes:UP000290289};
KW   Transferase {ECO:0000256|RuleBase:RU003633}.
FT   DOMAIN          46..247
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          257..406
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   DOMAIN          460..665
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          675..822
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
SQ   SEQUENCE   865 AA;  95521 MW;  EF8E0E684E60925B CRC64;
     MGYCHSFYRN LSTSPSLSNF NKSLLYICYL TCSMAPLVKN HVEPPHAKIL AIGTANPPNV
     YYQKDYPDFL FRVTKNEHRT DLREKKRYLY LTEEILNANP SIYTYGAPSL DVRQDMLNPE
     VPKLGQQAAL KAIKEWGQPI SKITHLIFCT ASCVDMPGAD FQLVKLLGLN PSVTRTMIYE
     AGCYAGATVL RLAKDFAENN EGARVLVVCA EITTVFFHGL TDTHLDILVG QALFADGASA
     VIVGANPEPE IERPLFEIVA CRQTIIPNSE HGVVANIREM GFNYYLSGEV PKFVGGSVVD
     FLTKTFEKVD GKNKDWNSLF FSVHPGGPAI VDQVEEQLGL KEGKLRATRH VLSEYGNMGA
     PSVHFILDEM RNKSIGEGKA TTGEGLEWGV MIGIGPGLTV ETAILRISSI SDCYKRKGVV
     PFILLEPFDS PSLSSFSKSL LYICSSTCPM APLVKNHGEH QHAKILAIGT ANPPNVYYQK
     DYPDFLFRVT KNEHRTDLRE KTRKRYLHLT EEILKANPSI YTYGAPSLDV RQDMLNPEVP
     KLGQQAALKA IKEWGQPISK ITHLIFCTAS CVDMPGADFQ LVKLLGLNPS VTRTMIYEAG
     CYAGATVLRL AKDFAENNEG ARVLVVCAEI TTVFFHGLTD THLDILVGQA LFADGASAVI
     VGANPEPKIE RPLFEIVACR QTIIPNSEHG VVANIREMGF TYYLSGEVPK FVGGNVVDFL
     TKTFEKVDGK NKDWNSLFFS VHPGGPAIVD QVEEQLGLKE GKLRATRHVL SEYGNMGAPS
     VHFILDDMRK KSIEEGKSTT GEGLEWGVVI GIGPGLTVET AIPQVSRFSN CYIRNGVVPF
     ILSQPFNSPS LFKFQQIPTL YLLFN
//