ID A0A498IMM4_MALDO Unreviewed; 1078 AA.
AC A0A498IMM4;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Cation-transporting P-type ATPase N-terminal domain-containing protein {ECO:0000259|SMART:SM00831};
GN ORFNames=DVH24_032753 {ECO:0000313|EMBL:RXH84470.1};
OS Malus domestica (Apple) (Pyrus malus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX NCBI_TaxID=3750 {ECO:0000313|EMBL:RXH84470.1, ECO:0000313|Proteomes:UP000290289};
RN [1] {ECO:0000313|EMBL:RXH84470.1, ECO:0000313|Proteomes:UP000290289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. HFTH1 {ECO:0000313|Proteomes:UP000290289};
RC TISSUE=Young leaf {ECO:0000313|EMBL:RXH84470.1};
RA Hu J.;
RT "A high-quality apple genome assembly.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXH84470.1}.
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DR EMBL; RDQH01000337; RXH84470.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498IMM4; -.
DR STRING; 3750.A0A498IMM4; -.
DR Proteomes; UP000290289; Chromosome 11.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005388; F:P-type calcium transporter activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 3.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF4; CALCIUM-TRANSPORTING ATPASE 1, ENDOPLASMIC RETICULUM-TYPE-RELATED; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000290289};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 99..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 806..829
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 880..902
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1002..1022
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1034..1054
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..116
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1078 AA; 118151 MW; 5A84CA89D622BFEB CRC64;
MTRDHIARRK KKLDPMGKGG QNYGKGESPN PIPIPKADHS FPAWSRDAKE CEDAFRVSRD
SGLSSEEVDN RRKVYGWNEL EKHEDQSMWK LLLDQLSDTL VRILLAAAII SFVLAWFDGE
EEKEITAFVE PLVIFLILIV NAIVGIWQES NAEKALEALK EIQSEQAAVI RDGRKVSNLS
AKELVPGDIV ELRVGDKVPA DMRVLNLVSS TFRVEQGSLT GESEAVSKSV KAVSENSDIQ
GKKCMVFAGT TVVNGHCVCL VTQIGMRTEI GQVHSQIQEA SQCENDTPLK KKLNEFGEIL
TMIIGVICAI VWLINVKYFL SWEIVDGLPT NFQFSFEKCT YYFKIAVALA VAAIPEGLPA
VITTCLALGT RRMAQKNALV RKLPSVETLG CTTVICSDKT GTLTTNQMAV AKLVAIGSRP
GTLRAFDVEG TTYNPFDGKI QDWPPAGDMD TNVQTIAKIA AVCNDAGVEL SGSHYVANGM
PTEAALKVLV EKMGVPEVLN TCFSSVGDLL RCSQLWNDID RRIATLEFDR DRKSMSVIVN
SGSGKNLLFV KGAVENVLER SSSIQLVDGS IVELDQKIRD LILGTLNEMS SSALRCLGFA
YKDDLPEFAM YNGDEDHPAH QLLLNPSNYS SIENKLVFVG MVGLRDPPRK EVRQAIEDCK
AAGIRVMVIT GDNKNTAEAI CREIGVFKPS EDISLKSLTG KEFIDHHDQK SYLRQSGGLL
FSRAEPRHKQ EIVRLLKEDG EVVAMTGDGV NDAPALKLAD IGIAMGIAGT EVAKEASDMV
LADDNFSTIV AAVGEGRSIY NNMKAFIRYM ISSNIGEVAS IFLTAALGIP EGMIPVQLLW
VNLVTDGPPA TALGFNPPDK DIMEKPPRRS NESLITPWIL FRYLVIGLYV GTATVGVFII
WYTHSSFLGI DLSQDGHSLV TYSQLANWGK CPSWEGFSPS NFTAGSQVFT FDTNPCEYFH
TGKIKASTLS LSVLVAIEMF NSLNALSEDG SLLTMPPWVN PWLLLAMSVS FGLHFLILYI
PFLANVFSIV PLSLNEWLLV LAAALPVILI DEILKFVGRC TSKLPDSPTI DRSKQKAE
//
