ID A0A498IRB0_MALDO Unreviewed; 800 AA.
AC A0A498IRB0;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
GN ORFNames=DVH24_017071 {ECO:0000313|EMBL:RXH86018.1};
OS Malus domestica (Apple) (Pyrus malus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX NCBI_TaxID=3750 {ECO:0000313|EMBL:RXH86018.1, ECO:0000313|Proteomes:UP000290289};
RN [1] {ECO:0000313|EMBL:RXH86018.1, ECO:0000313|Proteomes:UP000290289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. HFTH1 {ECO:0000313|Proteomes:UP000290289};
RC TISSUE=Young leaf {ECO:0000313|EMBL:RXH86018.1};
RA Hu J.;
RT "A high-quality apple genome assembly.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC ECO:0000256|RuleBase:RU000394}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXH86018.1}.
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DR EMBL; RDQH01000336; RXH86018.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498IRB0; -.
DR STRING; 3750.A0A498IRB0; -.
DR Proteomes; UP000290289; Chromosome 10.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd01366; KISc_C_terminal; 1.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47972:SF45; KINESIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR47972; KINESIN-LIKE PROTEIN KLP-3; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Coiled coil {ECO:0000256|SAM:Coils};
KW Microtubule {ECO:0000256|RuleBase:RU000394};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000290289}.
FT DOMAIN 438..779
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 127..424
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 20..39
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 523..530
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 800 AA; 90313 MW; 4C340A6AADDC6E2A CRC64;
MASRNQNRAP RSPFSKKSSL DEVPLDKRRR IETRKPEVPS SMGRQRPPLA VVKQDAAGTS
DIGSVEGSEC ANVEFTKEEV EALLVEKLKV KKFDHKGKAE QLADYSKRLK LCIKWLQEVE
EGHILEEEKL RNALASAEKK CADTEVEMRN KVDELNAVNS KLRENIATLE EKLAKEESEK
LDAIASHRSE KEARDAAEKL QASLSQKLEI VREEKLVADK KVSSYQDLYN RAQEYNKSLQ
QYNSKLQKDL ETATESLKRV EDEKRTVLET LSNLRVHNKA LQDELTKVTA SLDETLKQKE
LLDNEIKCLR GELQQVRDDR DRHAREIQDM RDQVVKYKEN TEMSCEELDR LMRKSKALEE
RDSSQKQEID TLKHELNAAN DKLKMVSQSA SETLTEFEEH KRIVQELQNR LAESELQILE
GEKLRKKLHN TILELKGNIR VFCRVRPLLP DDANATDAPV VSYPTGTEAL GRGLDLVQSG
QKFNFTFDKV FHHETSQQDV FVEISQLVQS ALDGYKVCIF AYGQTGSGKT YTMMGRPDAP
EQKGLIPRSL EQIFQTSQAL QAQGWKYKMQ ASMLEIYNEN IRDLLCTGRS SSADLSKTEN
GVCGKQYTIK HDANGNTYVS DLTIVDVCNI NQISSLLQQA AHSRSVGKTH MNEQSSRSHF
VFTLRISGIN ENTEQQVQGV LNLIDLAGSE RLSRSGATGE RLKETQAINK SLSSLSDVIF
ALAKKEDHVP FRNSKLTYLL QPCLGGDSKT LMVVNISPDS SSVGESLCSL RFAARVNACE
IGIPRRQTSM KPADNRLSYG
//
