ID A0A498JJ09_MALDO Unreviewed; 1277 AA.
AC A0A498JJ09;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=C2 domain-containing protein {ECO:0000259|PROSITE:PS50004};
GN ORFNames=DVH24_008030 {ECO:0000313|EMBL:RXH95530.1};
OS Malus domestica (Apple) (Pyrus malus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX NCBI_TaxID=3750 {ECO:0000313|EMBL:RXH95530.1, ECO:0000313|Proteomes:UP000290289};
RN [1] {ECO:0000313|EMBL:RXH95530.1, ECO:0000313|Proteomes:UP000290289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. HFTH1 {ECO:0000313|Proteomes:UP000290289};
RC TISSUE=Young leaf {ECO:0000313|EMBL:RXH95530.1};
RA Hu J.;
RT "A high-quality apple genome assembly.";
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 47 family.
CC {ECO:0000256|ARBA:ARBA00010271}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXH95530.1}.
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DR EMBL; RDQH01000332; RXH95530.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A498JJ09; -.
DR STRING; 3750.A0A498JJ09; -.
DR EnsemblPlants; mRNA:MD06G0065200; CDS:MD06G0065200.1; MD06G0065200.
DR Gramene; mRNA:MD06G0065200; CDS:MD06G0065200.1; MD06G0065200.
DR Proteomes; UP000290289; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd04022; C2A_MCTP_PRT_plant; 1.
DR CDD; cd08378; C2B_MCTP_PRT_plant; 1.
DR CDD; cd04019; C2C_MCTP_PRT_plant; 1.
DR Gene3D; 2.60.40.150; C2 domain; 3.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR047257; C2B_MCTP_PRT_plant.
DR InterPro; IPR047258; C2C_MCTP_PRT_plant.
DR InterPro; IPR040911; Exostosin_GT47.
DR InterPro; IPR013583; MCTP_C.
DR InterPro; IPR047259; QUIRKY-like.
DR PANTHER; PTHR31425:SF52; C2 CALCIUM_LIPID-BINDING PLANT PHOSPHORIBOSYLTRANSFERASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR31425; PHOSPHORIBOSYLANTHRANILATE TRANSFERASE ISOFORM 1; 1.
DR Pfam; PF00168; C2; 3.
DR Pfam; PF03016; Exostosin; 1.
DR Pfam; PF08372; PRT_C; 1.
DR SMART; SM00239; C2; 3.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 3.
DR PROSITE; PS50004; C2; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000290289};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 611..629
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 725..748
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..109
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 258..378
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 418..543
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 135..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1277 AA; 145282 MW; 4CF37041008573C9 CRC64;
MMNNLKLGVD VVGAHNLLPK DGQGSSNAFV ELYFDGQRFR TTIKEKDLNP VWNESFYFNI
SDPSNLHYLT LEAYVYNNVK ASYSRSFLGK ISLTGNSFVP YSDAVVLHYP LEKRGIFSRV
RGELGLKVYV TDDTSIRSST PVPNAESLAN ADPSAAHGHT EGVPNPVMNA LRNERAGTRH
SFHHLPHPSH DEQHQHRASS APDEHYVPKY EADQMKQEQP QPAKLVRMHS AASSQPVDFA
LKETSPYLGG GRVVGGRVIH GDKTASTYDL VERMYFLYVR VVKARELPAM DVTGSLDPYV
EVRIGNYRGI TKHFEKQQNP TWNQVFAFSK DRMQASVLEV VIKDKDLIKD DFVGLVRFDI
NEVPMRVPPD SPLAPEWYRL EDKKGEKIKS ELMLAVWIGT QADEAFSDAW HSDAATPVDS
TPAASTLIRS KVYHAPRLWY VRVNVIEAQD LFAAEKNRFP ESYVKVQLGN QVLKTKTLQA
RNLNPLWNED LLFVASEPFE DHLIISVEDR VGPGRDEIIG RVILPLNAVD RRADDRMIHS
RWFNLEKPVA VDIDQLKRDK FSSRLHLRVC LDGGYHVLDE STHYSSDLRP TAKQLWRPSI
GALLSWRDPR ASALFVTFCL IAALVMYVTP FQCGSTPTGG TGIADIPSTL AIREKPPGET
GIANISPALP TREKQNRIRP SPCKNLKPEA EQVQTSSFLT MVGVSMSKRK PKLPMQPAPK
ESCSCFLFLF KFLFRVPVAF FILLIYLWSS SATIFSGNIV HICVSSRKLN DHYCLSAGKT
QPKFEIPIPI VNHSSIYLYT LDKSLNLPLP SSPPLYRGNG STSPQSTVNG EKVRETAEVI
RDESEPVTMR NGENKDGEEQ VANAKKDVEE QMRLHRSWIS DKKQAGCEGR GVYVYDLPSK
FNFDLIGQCR DMVPWMDFCK YFKNEAMGEP IPKFGNGWYQ THQYSLEPIF HQRVMKHPCR
VYNEDEAKLF YIPFYGGLDI LRWHFKNVSS DVKDTLSLEL ITWLEKQRSW TKNSRKDHVI
VLGKISWDFR RKDRSWGTRF LEIDQMKNPV KLLIERQPWQ PNDIGIPHPT SFHPSSDDDI
MAWQWKILSS HRKQLVGFAG AERPGQAESI RSMLIKQCNP SSKNGNQCRF LDCGSGGCDQ
PETVIDLFLE SEFCLQPPGD SPTRKSLFDS LIAGCIPVLF DPFTAYYQYP WHLPEDHGKY
SVFVDQEEVR GMKVNVVEML MKISKEKRDD MRRFIVYELL PGLVYGDSNA KFEKFEDAFS
ITMSNLMERV TKLKLNV
//
