ID   A0A498JXD2_MALDO        Unreviewed;       668 AA.
AC   A0A498JXD2;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Fe2OG dioxygenase domain-containing protein {ECO:0000259|PROSITE:PS51471};
GN   ORFNames=DVH24_021578 {ECO:0000313|EMBL:RXH99776.1};
OS   Malus domestica (Apple) (Pyrus malus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX   NCBI_TaxID=3750 {ECO:0000313|EMBL:RXH99776.1, ECO:0000313|Proteomes:UP000290289};
RN   [1] {ECO:0000313|EMBL:RXH99776.1, ECO:0000313|Proteomes:UP000290289}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. HFTH1 {ECO:0000313|Proteomes:UP000290289};
RC   TISSUE=Young leaf {ECO:0000313|EMBL:RXH99776.1};
RA   Hu J.;
RT   "A high-quality apple genome assembly.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC       family. {ECO:0000256|ARBA:ARBA00008056}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RXH99776.1}.
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DR   EMBL; RDQH01000331; RXH99776.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A498JXD2; -.
DR   Proteomes; UP000290289; Chromosome 5.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR026992; DIOX_N.
DR   InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR   InterPro; IPR027443; IPNS-like_sf.
DR   InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR   PANTHER; PTHR47991:SF223; FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR47991; OXOGLUTARATE/IRON-DEPENDENT DIOXYGENASE; 1.
DR   Pfam; PF03171; 2OG-FeII_Oxy; 2.
DR   Pfam; PF12697; Abhydrolase_6; 1.
DR   Pfam; PF14226; DIOX_N; 1.
DR   PRINTS; PR00682; IPNSYNTHASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF51197; Clavaminate synthase-like; 2.
DR   PROSITE; PS51471; FE2OG_OXY; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Reference proteome {ECO:0000313|Proteomes:UP000290289}.
FT   DOMAIN          193..294
FT                   /note="Fe2OG dioxygenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51471"
SQ   SEQUENCE   668 AA;  75918 MW;  3F2263BEC4C1DF88 CRC64;
     MGEVDPAFIQ DPEHRPKLSA TEVKGIPLID LSLINSPHSV YDPRAFEGLV AEIGNACKDW
     GFFQVINHGR SAKGSKLLLG SSLRCLWRRR KIRRDEGNVL GYYDTEHTKN VRDWKEVFDF
     TVEEPTLVPA SPDPEDKEET EWYNQWPEYP PELRNACEEY AREVENLALK LMGLIALGLG
     LPKDRFNSYF KDQTSFLRLN HYPPCPSPQL ALGVGRHKDG GALTVLAQDD VGGLEVKRKT
     DGVWIRVKPT PNAFIINVGD VIQVWSNERY ESVEHRVIVN SEKERFSIPY YLNPAHYTQV
     EPLEELINEQ NPAKYKPYSW GKFITHRKLT QAKTLPLIDL SPINTPDNIS GPMHAKIDDA
     GGLEVKRKAD GEWIPPNLLS TSNIRTKGHA QEFRTILSND RYESLEHRVV VNSKKERFSI
     PFFVNPAHYT IVKPLEELAD EQNQAKYKPY NWGKFFSHRK LTDFKKNSAE NMQLCHFRQN
     LIPSISTFLI VLLLCVANEI ESAPTNPSKQ HFVLVHGSCF GAWSWYKLVT LIRSSGHNVT
     ALDLAASGVD PQQAKDLRSI SDYLKPLRDF MEAVDGKVIL VGHSLGGLAI SQAMERFPSK
     ISVAIFVTAL MSGPANISSL NKEVSSCTFL YCKKPHHITL MALFVTVINY RKIRLRRIKI
     QIFIKVVY
//